Factor X Deficiency: A Rare Case of Inherited Coagulation Disorder Presenting As Hemarthrosis
Keywords:
Hemarthosis, Factor X deficiency, Bleeding disorder
Abstract
Hemophilia due to factor VIII deficiency is most common inherited bleeding disorder in paediatric population. Hemarthrosis is initial manifestation in large number of patients. We are presenting a case of factor X deficiency who presented with knee hemarthrosis.
Downloads
Download data is not yet available.
References
1. Hilgartner MW MC Millan CW:Coagulation disorders. In Blood Diseases of Infancy and Childhood eds. Miller DR, Bachner RL, Mc Millan CW and Miller LP 5th edn. The C.V.Mosby Company St. Louis P. 894 1984.
2. Hossouna HI:Laboratory Evaluation of Hemostatic Disorders, Hematology Oncology Clinic of North America-Coagulation disorder II/W.B.Saunders, Philedelphia. Pp 1242-1243,December 1993.
3. Uprichard J, Perry DJ. Factor X deficiency. Blood Rev 2002; 16(2):97-110. [PubMed]
4. Hertzberg M. Biochemistry of factor X. Blood Rev 1994; 8(1):56-62. [PubMed]
5. Saligsohn U, White GC. Inherited deficiencies of coagulation factors II, V, VII, XI and XIII and the combined deficiencies of Factors V and VIII and of the Vitamin K dependent factors. In: Beutler E, Lichtman MA, Coller BS, Kipps TJ, Seligsohn U (editors) Williams Hematology (6th edition, International Edition).McGraw-Hill Medical Publishing Division. New York 2001. P 1617-38.
6. Kouides PA, Kulzer L. Prophylactic treatment of severe factor X deficiency with prothrombin complex concentrate. Haemophilia 2001; 7(2):220-3. [PubMed]
7. Bajaj SP, Joist NH. New insights into how blood clots: implications for the use of APTT and PT as coagulation screening tests and in monitoring of anticoagulant therapy. Semin Thromb Hemost 1999; 25(4):407-18. [PubMed]
8. Dalal A, Pradhan M , Agarwal S. Genetics of Bleeding Disorders . Int J Hum Genet 2006; 6(1): 27-32.
9. Anwar M, Hamdani SN, Ayyub M, Ali W. Factor X deficiency in North Pakistan . J Ayub Med Coll Abbottabad 2004; 16 (3):1-4. [PubMed]
10. Peyvandi F, Menegatti M, Santagostino E, Akhavan S, Uprichard J, Perry DJ, et al. Gene mutations and three-dimensional structural analyses in 13 families with severe factor X deficiency. Br J Haematol 2002; 117(3):685-92.
2. Hossouna HI:Laboratory Evaluation of Hemostatic Disorders, Hematology Oncology Clinic of North America-Coagulation disorder II/W.B.Saunders, Philedelphia. Pp 1242-1243,December 1993.
3. Uprichard J, Perry DJ. Factor X deficiency. Blood Rev 2002; 16(2):97-110. [PubMed]
4. Hertzberg M. Biochemistry of factor X. Blood Rev 1994; 8(1):56-62. [PubMed]
5. Saligsohn U, White GC. Inherited deficiencies of coagulation factors II, V, VII, XI and XIII and the combined deficiencies of Factors V and VIII and of the Vitamin K dependent factors. In: Beutler E, Lichtman MA, Coller BS, Kipps TJ, Seligsohn U (editors) Williams Hematology (6th edition, International Edition).McGraw-Hill Medical Publishing Division. New York 2001. P 1617-38.
6. Kouides PA, Kulzer L. Prophylactic treatment of severe factor X deficiency with prothrombin complex concentrate. Haemophilia 2001; 7(2):220-3. [PubMed]
7. Bajaj SP, Joist NH. New insights into how blood clots: implications for the use of APTT and PT as coagulation screening tests and in monitoring of anticoagulant therapy. Semin Thromb Hemost 1999; 25(4):407-18. [PubMed]
8. Dalal A, Pradhan M , Agarwal S. Genetics of Bleeding Disorders . Int J Hum Genet 2006; 6(1): 27-32.
9. Anwar M, Hamdani SN, Ayyub M, Ali W. Factor X deficiency in North Pakistan . J Ayub Med Coll Abbottabad 2004; 16 (3):1-4. [PubMed]
10. Peyvandi F, Menegatti M, Santagostino E, Akhavan S, Uprichard J, Perry DJ, et al. Gene mutations and three-dimensional structural analyses in 13 families with severe factor X deficiency. Br J Haematol 2002; 117(3):685-92.
CITATION
DOI: 10.17511/ijmrr.2014.i03.14
Published: 2014-06-30
How to Cite
1.
Sinha S, Barik S. Factor X Deficiency: A Rare Case of Inherited Coagulation Disorder Presenting As Hemarthrosis. Int J Med Res Rev [Internet]. 2014Jun.30 [cited 2024Jul.3];2(3):253- 255. Available from: https://ijmrr.medresearch.in/index.php/ijmrr/article/view/97
Section
Case Report
OAI - Open Archives Initiative
