Factor X Deficiency: A Rare Case of Inherited Coagulation Disorder Presenting As Hemarthrosis
Keywords:
Hemarthosis, Factor X deficiency, Bleeding disorder
Abstract
Hemophilia due to factor VIII deficiency is most common inherited bleeding disorder in paediatric population. Hemarthrosis is initial manifestation in large number of patients. We are presenting a case of factor X deficiency who presented with knee hemarthrosis.
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References
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2. Hossouna HI:Laboratory Evaluation of Hemostatic Disorders, Hematology Oncology Clinic of North America-Coagulation disorder II/W.B.Saunders, Philedelphia. Pp 1242-1243,December 1993.
3. Uprichard J, Perry DJ. Factor X deficiency. Blood Rev 2002; 16(2):97-110. [PubMed]
4. Hertzberg M. Biochemistry of factor X. Blood Rev 1994; 8(1):56-62. [PubMed]
5. Saligsohn U, White GC. Inherited deficiencies of coagulation factors II, V, VII, XI and XIII and the combined deficiencies of Factors V and VIII and of the Vitamin K dependent factors. In: Beutler E, Lichtman MA, Coller BS, Kipps TJ, Seligsohn U (editors) Williams Hematology (6th edition, International Edition).McGraw-Hill Medical Publishing Division. New York 2001. P 1617-38.
6. Kouides PA, Kulzer L. Prophylactic treatment of severe factor X deficiency with prothrombin complex concentrate. Haemophilia 2001; 7(2):220-3. [PubMed]
7. Bajaj SP, Joist NH. New insights into how blood clots: implications for the use of APTT and PT as coagulation screening tests and in monitoring of anticoagulant therapy. Semin Thromb Hemost 1999; 25(4):407-18. [PubMed]
8. Dalal A, Pradhan M , Agarwal S. Genetics of Bleeding Disorders . Int J Hum Genet 2006; 6(1): 27-32.
9. Anwar M, Hamdani SN, Ayyub M, Ali W. Factor X deficiency in North Pakistan . J Ayub Med Coll Abbottabad 2004; 16 (3):1-4. [PubMed]
10. Peyvandi F, Menegatti M, Santagostino E, Akhavan S, Uprichard J, Perry DJ, et al. Gene mutations and three-dimensional structural analyses in 13 families with severe factor X deficiency. Br J Haematol 2002; 117(3):685-92.
CITATION
DOI: 10.17511/ijmrr.2014.i03.14
Published: 2014-06-30
How to Cite
1.
Sinha S, Barik S. Factor X Deficiency: A Rare Case of Inherited Coagulation Disorder Presenting As Hemarthrosis. Int J Med Res Rev [Internet]. 2014Jun.30 [cited 2024Dec.27];2(3):253- 255. Available from: https://ijmrr.medresearch.in/index.php/ijmrr/article/view/97
Section
Case Report
OAI - Open Archives Initiative
