An Evaluating the Accuracy of Endoscopic diagnosis : A comparative analysis with Histopathology in Upper and Lower GI Tract Disorders

Smriti Rathore, Prashant Kumar Singh — Thu, 24 Jul 2025 00:00:00 +0530

ABSTRACT

Background: Endoscopy and histopathology are complementary tools in diagnosing gastrointestinal (GI) disorders. While endoscopy provides macroscopic visualization, histopathology offers definitive microscopic diagnosis. This study aims to evaluate the correlation between endoscopic findings and histopathological results in upper and lower GI disorders.

Objectives:

To assess the diagnostic correlation between endoscopic impressions and histopathological diagnosis.
To determine the accuracy of endoscopy in detecting various upper and lower GI tract pathologies.

Methods: A retrospective study was conducted on 200 patients undergoing upper GI endoscopy (UGIE) and Colonoscopy for GI symptoms. Endoscopic findings were documented and correlated with histopathology reports of biopsy specimens.

Results: Endoscopic and histopathological findings were consistent in 92% of upper GI cases and 90.6% of lower GI cases. Among 125 upper GI cases, 115 were concordant, and among 75 lower GI cases, 68 were concordant. Highest correlation was observed in cases of gastric ulcers, esophagitis, colorectal polyps, and inflammatory bowel disease (IBD) and malignancy.

Conclusion: Endoscopy is a reliable initial diagnostic tool. However, histopathological confirmation is essential, especially in cases with subtle or ambiguous endoscopic findings.

Keywords: Endoscopy, Histopathology, GI Disorders, Upper GI, Colonoscopy.

International Journal of Medical Research and Review

An Evaluating the Accuracy of Endoscopic diagnosis : A comparative analysis with Histopathology in Upper and Lower GI Tract Disorders