Serum Lipid Profile in Early Pregnancy as a Predictor of Preeclampsia

  • Dr. Urmila Singh M D, Department of Obstetrics and Gynecology, King George’s Medical University, Lucknow, Uttar Pradesh, India
  • Dr Sonali Yadav Ph.D, Department of Pathology, King George’s Medical University, Lucknow, Uttar Pradesh, India
  • Dr Seema Mehrotra M D, Department of Obstetrics and Gynecology, King George’s Medical University, Lucknow, Uttar Pradesh, India
  • Dr S M Natu Ph D, Department of Pathology, King George’s Medical University, Lucknow, Uttar Pradesh, India
  • Dr Kamlesh kumari M D, Department of Obstetrics and Gynecology, King George’s Medical University, Lucknow, Uttar Pradesh, India
  • Dr Yogendra Singh Yadav M D, Department of Paediatrics, King George’s Medical University, Lucknow, Uttar Pradesh, India
Keywords: Dyslipidemia, Lipid profile, Preeclampsia, Pregnancy

Abstract

Background: The study aimed to investigate the relationship between early pregnancy serum lipid concentrations and risk of preeclampsia. Material and

Methods: Serum lipid profile was measured enzymatically by standardized assay in 270 pregnant women between 13-20 weeks of gestation. Out of these total number 58 subjects developed preeclampsia (study group) while 212 subjects remained normotensive (control group).

Results: The mean serum level of total cholesterol (TC), triglycerides (TG), low density lipoprotein cholesterol (LDL-C) and very low density lipoprotein cholesterol (VLDL-C) was significantly higher in preeclamptic women as compared to normotensive pregnant women. While preeclamptic women showed significant fall in high density lipoprotein cholesterol HDL-C) level as compared to normal pregnant women.

Conclusion: The measurement of serum lipid profile in early pregnancy may serve as early predictor of preeclampsia.

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CITATION
DOI: 10.17511/ijmrr.2013.i02.03
Published: 2013-06-30
How to Cite
1.
Singh U, Yadav S, Mehrotra S, Natu SM, kumari K, Singh Yadav Y. Serum Lipid Profile in Early Pregnancy as a Predictor of Preeclampsia. Int J Med Res Rev [Internet]. 2013Jun.30 [cited 2024Dec.23];1(2):55-2. Available from: https://ijmrr.medresearch.in/index.php/ijmrr/article/view/9
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Original Article

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