Cannabis induced psychosis - an overview
Abstract
Psychosis is a condition where there is a loss of contact with reality with symptoms like delusions, hallucinations, paranoia, disorganized thinking & speech, loss of motivation, depression, anxiety & poor sleep. It can be associated with Schizophreniform disorder, Bipolar disorder, Schizoaffective disorder, Depression with psychotic features, Drug-induced psychosis, Organic psychosis or Post-traumatic stress disorder. Psychosis is so common that about 3 out of every 100 people will have a psychotic episode in their lifetime. The phases of psychosis include an initial Prodromal Phase where there is subtle changes in thinking, perception and behavior. During acute Phase full blown symptoms occur which may affect the individual's daily living. Later Recovery Phase starts.
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References
2. Verdoux H, Gindre C, Sorbara F, Tournier M, Swendsen JD. Effects of cannabis and psychosis vulnerability in daily life: an experience sampling test study.Psychol Med. 2003 Jan;33(1):23-32. [PubMed]
3. Arseneault L, Cannon M, Witton J, et al. Causal association between cannabis and psychosis: examination of the evidence. Br J Psychiatry. Jan 2004, 184 (2) 110-117; DOI: 10.1192/bjp.184.2.110.
4. Leweke FM, Koethe D. Cannabis and psychiatric disorders: it is not only addiction.Addict Biol. 2008 Jun;13(2):264-75. doi: 10.1111/j.1369-1600.2008.00106.x. [PubMed]
5. Ben Amar M, Potvin S. Cannabis and psychosis: what is the link?J Psychoactive Drugs. 2007 Jun;39(2):131-42. [PubMed]
6. Dean B, Sundram S, Bradbury R, Scarr E, Copolov D. Studies on [3H]CP-55940 binding in the human central nervous system: regional specific changes in density of cannabinoid-1 receptors associated with schizophrenia and cannabis use.Neuroscience. 2001;103(1):9-15. [PubMed]
7. Morgan CJ, Freeman TP, Powell J, Curran HV.AKT1 genotype moderates the acute psychotomimetic effects of naturalistically smoked cannabis in young cannabis smokers.Transl Psychiatry.2016Feb16;6:e738. doi: 10.1038/tp.2015.219. [PubMed]
8. Danovitch I, Gorelick DA. State of the art treatments for cannabis dependence.PsychiatrClin North Am. 2012 Jun;35(2):309-26. doi: 10.1016/j.psc.2012.03.003. Epub 2012 Apr 10. [PubMed]
9. Rigter H, Pelc I, Tossmann P, Phan O, Grichting E, Hendriks V, et al. INCANT: A transnational randomized trial of multidimensional family therapy versus treatment as usual for adolescents with cannabis use disorder. BMC Psychiatry 2010;10:28. doi.org/10.1186/1471-244X-10-28.
11. Leweke FM, Piomelli D, Pahlisch F, Muhl D, Gerth CW, Hoyer C, et al. Cannabidiol enhances anandamide signalling and alleviates psychotic symptoms of schizophrenia. Transl Psychiatry. 2012 Mar 20;2:e94. doi: 10.1038/tp.2012.15.
12. Pal V. S, Rastogi P, Chauhan A, Niranjan V. Cross-Sectional study of differences in phenomenology of acute psychosis with or without cannabis. Int J Med Res Rev 2017;5(10):883-887.doi:10.17511/ijmrr. 2017.i10.02.
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