Profile of Congenital Heart Disease in childhood
Abstract
Introduction: Globally, the prevalence of congenital heart diseases is 3.7 to 17.5 per 1000 live births; in India, it is 2.25-5.2 per 1000 children. The profile of Congenital Heart Disease varies with the age group; Simple heart defects are common at all ages, whereas serious defects are seen in autopsy. This study aims to assess the clinical profile of Congenital Heart Disease.
Materials and Methods: The study was conducted in Department of Pediatrics, Bundelkhand Medical College, Sagar, India. It was a prospective study of cases attending the pediatric outpatient and inpatient department, as described by inclusion criteria over a period of 1 year. 100 cases could be included. Clinical assessment, 2 D Echocardiography and Color Doppler were used for diagnosis.
Results: A prevalence of 15.38 per 1000 patients was observed. The commonest acyanotic Congenital Heart Disease was Ventricular septal defect (29%), followed by Atrial septal defect (13%) and Patent ductus arteriosus (5%). The commonest Cyanotic Congenital Heart Disease was Tetralogy of Fallot (26%) followed by Transposition of Great Arteries (9%) and Total anomalous Pulmonary Venous Connection (4%). Most children with heart disease were diagnosed between 1-5 years of age, acyanotic heart disease presenting at a mean age of 11.5 months, cyanotic heart disease with decreased pulmonary blood flow at 10.5 months and cyanotic heart disease with increased pulmonary blood flow at 5 months.
Conclusions: Heart diseases are a significant cause of morbidity and mortality in children. Early diagnosis and early referral for definitive surgery is necessary to improve their quality of life.
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References
2. Ferencz C, Rubin JD, McCarter RJ, Brenner JI, Neill CA, Perry LW. Congenital Heart Disease: Prevalence at live birth. The Baltimore-Washington Infant Study. Am J Epidem 1985; 121:31-6. [PubMed]
3. Brassili A, Mokhtar SA, Dabous NI, Zaher SR, Mokhtar MM, Zaki A. Congenital heart disease among school children in Alexandria, Egypt: an overview on prevalence and relative frequencies. J Trop Pediatr. 2000:46:357-62. [PubMed]
4. Kapoor R, Gupta S. Prevalence of Congenital Heart Disease, Kanpur, India. Indian Pediat 2008;45:309-11. [PubMed]
5. Vashishta VM, Kalra A, Kalra K, Jain VK. Prevalence of congenital heart disease. Indian Pediatr 1993; 30: 1337-40. [PubMed]
6. Khalil A, Aggarwal R, Thirupuram S, Arora R. Incidence of congenital heart disease among hospital live births in India. Indian Pediatr 1994; 31: 519-24. [PubMed]
7. Gupta J, Gupta ML, Parihar A, Gupta CD, Epidemiology of Congenital & Rheumatic Heart Disease in School Children. J. Ind. Med. Association. 1992;90:57-9. [PubMed]
8. Lawn JE, Cousens S, Zupan J.4 million neonatal deaths: When? Where? Why? Lancet 2005; 365:891-900. [PubMed]
9. Saxena A. Congenital Heart Disease in India: A status Report. Ind. Jrnl. Paed.Vol. 72, July 2005.595-8. [PubMed]
10. Kinare SG, Sharma S. Congenital Heart Disease in 1st year of life (an autopsy study of 270 cases). Ind. Jrnl. Paed 1981:48:745-754. [PubMed]
11. Hoffmann JIE, Samuel Kaplan. Incidence of congenital heart disease (Review article) J.Am Coll. Cardiology 2002; 39:1890-1900. [PubMed]
12. Warnes CA, Liberthson R, Gordon K. Danielson Jr.,Dore A, Harris L et al. Task Force 1: the changing profile of congenital heart disease in adult life. J Am Coll Cardiol. 2001; 37:1170-1175. [PubMed]
13. Dickinson DF, Arnold R, Wilkinson JL. Congenital heart disease among 160,480 live born children in Liverpool, 1960 to 1969. Implications for surgical treatment. Br Heart J 1981; 46:55-62. [PubMed]
14. Fixler DE, Pastor P, Chamberlin M, Sigman E, Eifler CW. Trends in congenital heart disease in Dallas county births 1971-1984. Circulation 1990; 81:137-42. [PubMed]
15. Sung RY, So LY, Ng HK, Ho JK, Fok TF. Echocardiography as a tool for determining the incidence of congenital heart disease in newborn babies: a pilot study in Hong Kong. Int J Cardiol 1991; 30:43-7. [PubMed]
16. Meberg A, Otterstad JE, Froland G, Sorland S, Nitter-Hauges. Increasing incidence of ventricular septal disease caused by improved detection rate. Acta Paediatr 1994; 83:653-7. [PubMed]
17. Hassan I, Haleem AA, Bhutta ZA. Profile and risk factors for congenital heart disease. J Pak Med assoc 1997; 47:78-81. [PubMed]
18. Alabdulgadar AA. Congenital Heart Disease in 740 subjects, epidemiological aspects. Ann Trop Paediatr 2001; 21:111-8. [PubMed]
19. Mclaren MJ, Lachman AS, Barlow JB. Prevalence of Congenital Heart Disease in Black Schoolchildren of Sourno,Johhanesberg. Br Heart Jrnl, 1979, May;41(5):554-8. [PubMed]
20. Oloron DPM, Ibarra CR, de Aguilar VA.Incidence of Congenital Heart Disease in Navvara(1989-1998) Revista Espanola de Cardiologia 2005 Dec(58); 12:1428-34. [PubMed]
21. Manchandha SS, Sachdev KK. Morbidity and mortality in children in Northern India (Punjab). Indian J Pediat 1962; 29:333-50. [PubMed]
22. Gupta S, Puri RK, Indira OC, Datta SP. Morbidity in children under 14 in South India. Indian Pediat 1968;5:485-97. [PubMed]
23. Bidwai PS, Mahajan CM, Walia BN, Berry JN. Congenital heart diseases in Childhood - A Clinical Study. Indian Pediatri 1971; 7:691-4. [PubMed]
24. Verma KC, Chabbra P, Magotra ML. A clinical study on prevalence of Heart Disease in children in Jammu & Kashmir area. Indian Paediatr 1979; 16:597-606. [PubMed]
25. Menache CC, du Plessis AJ, Wessel DL, Jonas RA, Newburger JW. Current incidence of acute neurologic complications after open-heart operations in children. Ann Thorac Surg 2002; 73:1752-8. [PubMed]
26. Khalil A. Congenital heart disease. In: Essentials of Pediatrics Cardiology, New Delhi 2003; 71-89.
27. Thakur JS, Negi PC, Ahluvalia SK, Sharma R, Bharadwaj R. Congenital Heart Disease in School children in Simla Hills. Indian Heart Journal 1995; 47:232-5. [PubMed]
28. Chadha SL, Singh N, Shukla DK. Epidemiological study of congenital heart disease. Indian J Pediatr. 2001; 68: 507-10. [PubMed]
29. Tefuarani N, Hawker R, Vince J, Sleigh A, Williams G. Congenital heart disease in Papua New Guinean children. Ann Trop Paediatr. 2001; 21:285-92. [PubMed]
30. Rahim F, Younas M, Gandapur AJ & Talat .A Pattern of congenital heart diseases in children at tertiary care center in Peshawar. Pak J Med Sci. 2003, 19(1)19-22.
31. ManBahadur KC, Sharma D, Shrestha MP, Gurung S, Rajbhandari S, Malla R,et al Prevalence of Rheumatic and Congenital Heart Disease in Schoolchildren of Kathmandu Valley in Nepal. Indian Heart J 2003; 55: 615–8. [PubMed]
32. Gupta S, Puri RK, Indira OC, Datta SP. Morbidity in children under 14 in South. Indian Pediat.1968; 5:485-497. [PubMed]
33. Bernstein.D. Acyanotic congenital heart disease. In. Nelson textbook of Pediatrics.18Edn. Ed: Kliegman R.M., Behrman R.E., Jenson H.B., Stanton B.F. Saunders. New Delhi.2007; 2:424:1883.
34. Sani MU, Mukhtar-Yola, Karaye KM. Spectrum of Congenital Heart Disease in a Tropical environment: An Echocardiographic Study. Jrnl of National Med Association. 2007(June); 99:6:665-9. [PubMed]
35. Varan B, Tokel K, Yilmaz G. Malnutrition & growth failure in cyanotic & Cyanotic Heart Diseases with & without pulmonary hypertension. Archives Dis Child 1999(July): 81: 49-52.
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