A study of the pain score following TRUS guided prostate biopsy with and without periprostatic lignocaine infiltration
Abstract
Introduction: Prostate cancer is one of the most common cancers in Western countries and is now increasing worldwide. Transrectal ultrasound guided prostate needle biopsy (TRUS) is the standard procedure to diagnose or exclude prostate cancer. TRUS-guided biopsy is associated with several complications and discomfort. We evaluated painless yet less invasive prostate biopsy.
Material and Methods: A randomised xwas conducted in 30 consecutive men divided into two groups. Group I consisted of fifteen patients who did not receive any analgesia, and another fifteen constituted study group, Group II, who received periprostatic infiltration of 1 % lignocaine. Patient with suspected DRE findings or elevated PSA or both were advised to undergo TRUS guided prostate biopsy. Pain intensity during the procedure was evaluated using Visual Analogue Scale. A visual analog scale was used to assess the pain score. Statistical analysis of pain scores was performed using the Student t test. Chi-square/ Fisher Exact test was used to find the significance of study parameters on categorical scale between two.
Results: In Group 2, there was a marked reduction in the pain experienced during the procedure. The Chi-squared test for trend showed a significant association between the periprostatic infiltration of 1 % lignocaine and reduction in pain on probe insertion and on taking the biopsy (P = 0.0001).
Conclusion: The use of periprostatic infiltration of lignocaine before taking the needle biopsy significantly reduces the pain experienced by the patient during TRUS-guided prostate biopsy.
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References
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