Eighth Nerve Dysfunction in Type 2 Diabetes Mellitus
Abstract
Introduction: Hearing impairment is one of the under-recognized complications of diabetes that affects the cognitive performance and quality of life. The study was conducted to estimate the prevalence of hearing impairment and analyze the type, degree and pattern of hearing impairment in diabetic population.
Materials and Methods: The study was conducted as a case-control study including 50 diabetic patients and 20 healthy individuals after exclusion of confounding factors. Hearing assessment was done using pure tone audiometry.
Results: The prevalence of hearing impairment in diabetics of age 35-65 years was 74% compared to normal population (15%). 7 out of 13 diabetic patients in the age group of 35-45, 19 out of 37 diabetics in the age group of 45-55 & 11 out of 13 diabetics in the age group of 55-65 had hearing impairment. 9 out of 12 diabetic patients having HbA1c of < 7 and 28 out of 38 diabetic patients having HbA1c of >7 had hearing impairment. 21 out of 27 patients with diabetes duration of <1 year, 6 out of 11 patients with diabetes duration of 1-5 years, and 10 out of 12 patients with diabetes duration >5years had hearing impairment. Out of 37 diabetic patients who had hearing impairment, 24 (64%) had diabetic neuropathy.
Conclusion: Eighth nerve dysfunction is common among diabetics. Its prevalence among the diabetics increases with age and positively correlates with the duration of diabetes and presence of diabetic peripheral neuropathy. However, its prevalence did not show positive correlation with the HbA1c levels.
Downloads
References
Corriere M, Rooparinesingh N, Kalyani RR. Epidemiology of Diabetes and Diabetes Complications in the Elderly: An Emerging Public Health Burden. Current diabetes reports. 2013;13(6): doi: https://doi.org/10.1007/s11892-013-0425-5.
Simpson AN, Simpson KN, Dubno JR. Health-related quality of life in older adults: Effects of hearing loss and common chronic conditions. Healthy aging research. 2015;4:4. doi: https://dx.doi.org/10.12715%2Fhar.2015.4.4.
Deal JA . Betz J, Yaffe K, Harris T, Purchase-Helzner E, Satterfield S, Pratt S, Govil N, Simonsick EM, Lin FR; Health ABC Study Group. Hearing Impairment and Incident Dementia and Cognitive Decline in Older Adults: The Health ABC Study. J Gerontol A Biol Sci Med Sci. 2016; Apr 12.doi: https://doi.org/10.1093/gerona/glw069.
Nageris B, Hadar T, Feinmesser M, Elidan J. Cochlear histopathologic analysis in diabetic rats. Am J Otol. 1998 Jan;19(1):63-5.
Rózańska-Kudelska M, Chodynicki S, Kinalska I, Kowalska. Hearing loss in patients with diabetes mellitus type II. Otolaryngol Pol. 2002;56(5):607-10.
de España R, Biurrun O, Lorente J, Traserra J. Hearing and diabetes. ORL J Otorhinolaryngol Relat Spec. 1995 Nov-Dec;57(6):325-7.
Tay HL, Ray N, Ohri R, Frootko NJ. Diabetes mellitus and hearing loss. Clin Otolaryngol Allied Sci. 1995 Apr; 20(2):130-4.
Weng SF, Chen YS, Hsu CJ, Tseng FY. Clinical features of sudden sensorineural hearing loss in diabetic patients. Laryngoscope. 2005 Sep;115(9):1676-80.
http://www.schwerhoerigen-netz.de/RATGEBER/HOERGERAETE/PDF/who-grades-hearing.pdf
Elamin A, Fadlallah M, Tuevmo THearing loss in children with type 1 diabetes. Indian Pediatr. 2005 Jan;42(1):15-21.
Oskun Durmus, Sertac Yetiser, and Ozlem Durmus. Auditory brainstem evoked responses in insulin-dependent (ID) and non-insulin-dependent (NID) diabetic subjects with normal hearing. International Journal of Audiology 2004 Vol. 43, Iss. 1
Wackym PA, Linthicum FH Jr. Diabetes mellitus and hearing loss: clinical and histopathologic relationships. Am J Otol. 1986 May;7(3):176-82.
A. Axelsson and S.E. Fagerberg. Auditory Function in Diabetics Acta Oto-Laryngologica. 1968 Vol. 66 , Iss. 1-6.
Kakarlapudi V, Sawyer R, Staecker H.The effect of diabetes on sensorineural hearing loss. Otol Neurotol. 2003 May;24(3):382-6.
Dalton DS1, Cruickshanks KJ, Klein R, Klein BE, Wiley TL.Association of NIDDM and hearing loss. Diabetes Care. 1998 Sep;21(9):1540-4.
Xu J, Liu C, Lian N, Yang Y, Tang X. [The status of auditory function in auditory neuropathy]. Lin Chuang Er Bi Yan Hou Ke Za Zhi. 2002 Jan;16(1):9-12.
OAI - Open Archives Initiative
