Sickle cell disease in the tribal population attending tertiary referral centre in Surguja district of Chhattisgarh

  • Dr. Mahasweta Mallik Department of Pathology, Associate Professor, Government, Medical College, Ambikapur, India
  • Dr. Alka Singh Department of Pathology, Assistant Professor, Government Medical, College, Ambikapur, India
  • Dr. Sujata Mallick Department of Pathology, Assistant Professor, KPC Medical College, Jadavpur, Kolkata, West Bengal, India
Keywords: Sickle cell disease, Sickle cell Anaemia (Homozygous), Sickle Cell Trait ( Heterozygyous), Tribal Population

Abstract

Background: sickle cell anaemia is a haemoglobin disorder which is autosomal recessive. As it is inherited disorder it is prevalent more in tribal population of India. Surguja district of Chhattisgarh also has a predominance o of tribal population.

Aim: Aim of this study is to find the incidence of sickle cell disease in the tribal population attending the tertiary referral hospital of surguja district.

Material and method: This is a retrospective study of a span of 3years from April 2013 to March 2016. A total of 5489 anaemic patients were tested.

Result: out of 5489 anaemic patients 399 were positive for sickle cell.

Conclusion: Education and counselling should be done to prevent sickle cell disease among the tribal of surguja district of chattisgarh.

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References

Bush RL, Pevec WC, Holcroft JW. A prospective, randomized trial limiting perioperative red blood cell transfusions in vascular patients. Am J Surg. 1997 Aug;174(2):143-8.doi: https://doi.org/10.1016/s0002-9610(97)00073-1.

Vincent JL, Baron JF, Reinhart K, Gattinoni L, Thijs L, Webb A, Meier-Hellmann A, Nollet G, Peres-Bota D; ABC (Anemia and Blood Transfusion in Critical Care) Investigators. Anemia and blood transfusion in critically ill patients. JAMA. 2002 Sep 25;288(12):1499-507.doi: https://doi.org/10.1001/jama.288.12.1499.

Masom VR, Sickle cell anaemia, severe anaemia with remarkable elongated shaped red blood cells. J Am Med Assoc 1922 Oct:79:1318-20.doi: https://doi.org/10.1001/jama.1922.02640160038012.

Claster S, Vichinsky EP. Managing sickle cell disease. BMJ. 2003 Nov 15;327(7424):1151-5.doi: https://doi.org/10.1136/bmj.327.7424.1151.

Saunthararajan Y,Vichinsky EP. Sickle cell disease: Clinical features and management. In: Hoffman R, Benz EJ Jr, Silberstein LE. Heslop HE, Weitz JI, editors. Haematology: Basic principles and Practice, 6th edition, Ch.40, Philadelphia, PA: Saunders Elsevier:2012.

Herrick JB. Peculiar elongated and sickle shaped red blood corpuscles in a case of severe anaemia. Arch Intern Med 1910: 6:517-21. Cited from Bridges KR. A brief history of sickle cell disease. April 2002. Available from: http://.Innvista.com/health/ailments/anaemias/sickhist.htm.

Lehmann H, Cutbush M. Sickle-cell trait in southern India. Br Med J. 1952 Feb 23;1(4755):404-5.doi: https://dx.doi.org/10.1136%2Fbmj.1.4755.404.

Census of India 2011. Office of the Registrar General and Census Commissioner.Ministry of home Affairs, Govt of India. Available from: http://www.censusindia.gov.in. accessed on March 27, 2015.

Stuart MJ, Nagel RL. Sickle-cell disease. Lancet. 2004 Oct 9-15;364(9442):1343-60.doi: https://doi.org/10.1016/s0140-6736(04)17192-4.

Rees DC, Williams TN, Gladwin MT. Sickle-cell disease. Lancet. 2010 Dec 11;376(9757):2018-31. doi: https://doi.org/10.1016/S0140-6736(10)61029-X. Epub 2010 Dec 3.

Surve RR,Mukherjee MB, Kate SL, Nagtilak SB, et al. Detection of beta S gene: An evaluation of solubilitytest against automated chromatography and haemoglobin electrophoresis. Br J Biomed sci 2000;57(4):292-4.

Allison AC. Protection afforded by sickle-cell trait against subtertian malareal infection. Br Med J. 1954 Feb 6;1(4857):290-4.doi: https://dx.doi.org/10.1136%2Fbmj.1.4857.290.

Deshmukh VV. Deficiency of erythrocyte glucose-6-phosphate dehydrogenase and sickle cell trait, a survey at Aurangabad, Maharashtra. Ind J Med Res 1968;56 (6): 821-825.

Urade BP. Sickle cell gene(HbS). Scenario in Tribal India. J health Med Inform, July 2012, 3:114. Doi: https://doi.org/10.4172/2157-7420.1000114.

Sickle cell disease in the tribal population attending tertiary referral centre in Surguja district of Chhattisgarh
CITATION
DOI: 10.17511/ijmrr.2016.i12.24
Published: 2016-12-31
How to Cite
1.
Mallik M, Singh A, Mallick S. Sickle cell disease in the tribal population attending tertiary referral centre in Surguja district of Chhattisgarh. Int J Med Res Rev [Internet]. 2016Dec.31 [cited 2021Jun.18];4(12):2223-5. Available from: https://ijmrr.medresearch.in/index.php/ijmrr/article/view/792
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Original Article