Sickle cell disease in the tribal population attending tertiary referral centre in Surguja district of Chhattisgarh

  • Dr. Mahasweta Mallik Department of Pathology, Associate Professor, Government, Medical College, Ambikapur, India
  • Dr. Alka Singh Department of Pathology, Assistant Professor, Government Medical, College, Ambikapur, India
  • Dr. Sujata Mallick Department of Pathology, Assistant Professor, KPC Medical College, Jadavpur, Kolkata, West Bengal, India
Keywords: Sickle cell disease, Sickle cell Anaemia (Homozygous), Sickle Cell Trait ( Heterozygyous), Tribal Population

Abstract

Background: sickle cell anaemia is a haemoglobin disorder which is autosomal recessive. As it is inherited disorder it is prevalent more in tribal population of India. Surguja district of Chhattisgarh also has a predominance o of tribal population.

Aim: Aim of this study is to find the incidence of sickle cell disease in the tribal population attending the tertiary referral hospital of surguja district.

Material and method: This is a retrospective study of a span of 3years from April 2013 to March 2016. A total of 5489 anaemic patients were tested.

Result: out of 5489 anaemic patients 399 were positive for sickle cell.

Conclusion: Education and counselling should be done to prevent sickle cell disease among the tribal of surguja district of chattisgarh.

Downloads

Download data is not yet available.

References

Bush RL, Pevec WC, Holcroft JW. A prospective, randomized trial limiting perioperative red blood cell transfusions in vascular patients. Am J Surg. 1997 Aug;174(2):143-8.doi: https://doi.org/10.1016/s0002-9610(97)00073-1.

Vincent JL, Baron JF, Reinhart K, Gattinoni L, Thijs L, Webb A, Meier-Hellmann A, Nollet G, Peres-Bota D; ABC (Anemia and Blood Transfusion in Critical Care) Investigators. Anemia and blood transfusion in critically ill patients. JAMA. 2002 Sep 25;288(12):1499-507.doi: https://doi.org/10.1001/jama.288.12.1499.

Masom VR, Sickle cell anaemia, severe anaemia with remarkable elongated shaped red blood cells. J Am Med Assoc 1922 Oct:79:1318-20.doi: https://doi.org/10.1001/jama.1922.02640160038012.

Claster S, Vichinsky EP. Managing sickle cell disease. BMJ. 2003 Nov 15;327(7424):1151-5.doi: https://doi.org/10.1136/bmj.327.7424.1151.

Saunthararajan Y,Vichinsky EP. Sickle cell disease: Clinical features and management. In: Hoffman R, Benz EJ Jr, Silberstein LE. Heslop HE, Weitz JI, editors. Haematology: Basic principles and Practice, 6th edition, Ch.40, Philadelphia, PA: Saunders Elsevier:2012.

Herrick JB. Peculiar elongated and sickle shaped red blood corpuscles in a case of severe anaemia. Arch Intern Med 1910: 6:517-21. Cited from Bridges KR. A brief history of sickle cell disease. April 2002. Available from: http://.Innvista.com/health/ailments/anaemias/sickhist.htm.

Lehmann H, Cutbush M. Sickle-cell trait in southern India. Br Med J. 1952 Feb 23;1(4755):404-5.doi: https://dx.doi.org/10.1136%2Fbmj.1.4755.404.

Census of India 2011. Office of the Registrar General and Census Commissioner.Ministry of home Affairs, Govt of India. Available from: http://www.censusindia.gov.in. accessed on March 27, 2015.

Stuart MJ, Nagel RL. Sickle-cell disease. Lancet. 2004 Oct 9-15;364(9442):1343-60.doi: https://doi.org/10.1016/s0140-6736(04)17192-4.

Rees DC, Williams TN, Gladwin MT. Sickle-cell disease. Lancet. 2010 Dec 11;376(9757):2018-31. doi: https://doi.org/10.1016/S0140-6736(10)61029-X. Epub 2010 Dec 3.

Surve RR,Mukherjee MB, Kate SL, Nagtilak SB, et al. Detection of beta S gene: An evaluation of solubilitytest against automated chromatography and haemoglobin electrophoresis. Br J Biomed sci 2000;57(4):292-4.

Allison AC. Protection afforded by sickle-cell trait against subtertian malareal infection. Br Med J. 1954 Feb 6;1(4857):290-4.doi: https://dx.doi.org/10.1136%2Fbmj.1.4857.290.

Deshmukh VV. Deficiency of erythrocyte glucose-6-phosphate dehydrogenase and sickle cell trait, a survey at Aurangabad, Maharashtra. Ind J Med Res 1968;56 (6): 821-825.

Urade BP. Sickle cell gene(HbS). Scenario in Tribal India. J health Med Inform, July 2012, 3:114. Doi: https://doi.org/10.4172/2157-7420.1000114.

Sickle cell disease in the tribal population attending tertiary referral centre in Surguja district of Chhattisgarh
CITATION
DOI: 10.17511/ijmrr.2016.i12.24
Published: 2016-12-31
How to Cite
1.
Mallik M, Singh A, Mallick S. Sickle cell disease in the tribal population attending tertiary referral centre in Surguja district of Chhattisgarh. Int J Med Res Rev [Internet]. 2016Dec.31 [cited 2024Apr.25];4(12):2223-5. Available from: https://ijmrr.medresearch.in/index.php/ijmrr/article/view/792
Section
Original Article