Uterine artery Doppler as a predictor of pre eclampsia - hospital based study
Abstract
Aim: Study of early second trimester (13-16wks) uterine artery Doppler as predictor of pre eclampsia.
Objective: To study whether early changes in uterine artery Doppler have better predictive value for preeclampsia as compared to gestational hypertension. To analyze the maternal and fetal outcome in cases with pre eclampsia vs gestational hypertension.
Material & Methods: From 2009 to 2011, we conducted an institutional based study among 100 pregnant women. Uterine artery Doppler was done in the women in early second trimester during the antenatal visits at Niloufer Hospital. We measured and recorded the BP, urine analysis, complete blood work done in every antenatal visit. These women were followed up to their delivery. Data were analyzed and p<0.05 was considered significant.
Results: Pre eclampsia developed in 31.25% of the pregnant women with bilateral uterine artery notching at 13-16 weeks of gestational age Odds ratio of patients developing hypertension with uterine artery notching is 6.6. Chi-square = 11.8, P value < 0.0005 (significant). This study has a sensitivity of 71.42%, specificity of 74.41%, positive predictive value of 31.25% and negative predictive value of 94.11% in predicting onset of preeclampsia in pregnancy.
Conclusion: Uterine artery Doppler should be done routinely in all pregnant women as risk factors can be identified at an early stage where timely intervention can reduce the maternal and neonatal complications.
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References
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