Comparison of midazolam versus clonazepam as premedication scheduled for elective abdominal hysterectomies

  • Dr Neeru Bala MD Psychiatry, Assistant Professor, Department of Psychiatry, Government Medical College, Amritsar (Punjab), India-143001
  • Dr Hardip Singh MD Medicine, Assistant Professor, Department of Medicine, Government Medical College, Amritsar (Punjab), India-143001
  • Dr Joginder Pal Attri MD Anaestheisa, Associate Professor, Department of Anaesthesia, Government Medical College, Amritsar (Punjab), India-143001
  • Dr Lipsy Bansal Junior Resident, Department of Anaesthesia, Government Medical College, Amritsar (Punjab), India-143001
  • Dr Sukhman Kaur Junior Resident, Department of Anaesthesia, Government Medical College, Amritsar (Punjab), India-143001
Keywords: Hamilton anxiety rating scale, Clonazepam, Midazolam, Sedation, Abdominal hysterectomy

Abstract

Background and aim: Anxiety is one of the most common problem which affect the patient during surgical procedures. Thus, anxiolytics have a primary role as premedication preoperatively. With this background, we designed this study to compare anxiolytic effects of oral midazolam and oral clonazepam.

Methods: Study was carried out in 80 patients scheduled for elective Abdominal hysterectomy and were divided into group of 40 each. Group M 40 patients were given Tab Midazolam 10 mg, 45 min before surgery. Group C of 40 patients were given Tab Clonazepam 2 mg, 45 min before surgery with a sip of water. All hemodynamic parameters, sedation score, satisfactory score, Hamitlon Anxiety Rating Scale were noted. The patient characteristics were analysed using “Chi-square test” and inter group comparison of the parametric data was done using the “unpaired t-test using software IBM SPSS 17.0.

Results: Clonazepam is better anxiolytic than midazolam and has longer duration of anxiolytic effects and with minimal side effects and better hemodynamic stability than midazolam.

Conclusion: Tab Clonazepam can be used as premedication to allay anxiety in the patients undergoing elective surgeries.

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Comparison of midazolam versus clonazepam as premedication scheduled for elective abdominal hysterectomies
CITATION
DOI: 10.17511/ijmrr.2016.i08.09
Published: 2016-08-31
How to Cite
1.
Bala N, Singh H, Pal Attri J, Bansal L, Kaur S. Comparison of midazolam versus clonazepam as premedication scheduled for elective abdominal hysterectomies. Int J Med Res Rev [Internet]. 2016Aug.31 [cited 2024Mar.29];4(8):1330-4. Available from: https://ijmrr.medresearch.in/index.php/ijmrr/article/view/649
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Original Article