A study of CD4 count and cervical epithelial abnormality in HIV positive women

  • Dr. Varalakshmi KP Associate Professor; Department of Pathology; Government Medical College Anantapuramu, Andhra Pradesh, India
  • Dr. R. Sujeeva Swapna Assistant Professor; Department of Pathology; Government Medical College Anantapuramu, India
  • Dr. Hariharanada Sarma Senior Consultant Pathologist, RDT Hospital Bathalapalli; Ananthapuramu District, India
  • Dr. Monoranjan Consultant, RDT Hospital Bathalapalli, Ananthapuramu District, India
  • Dr. Neeraja M Professor, Department of Pathology; Government Medical College Anantapuramu, Andhra Pradesh, India
Keywords: Cervical screening, HSIL, LSIL, ASCUS, CD4 T-cell Count

Abstract

Introduction: Cervical epithelial cell abnormalities (ECA) can result in cervical cancer which is the most common cause of cancer related death especially in developing countries. The aim of the present study is to find the association of CD4 count and Cervical epithelial abnormality in HIV positive women.

Materials and Methods: A study of association between cervical epithelial abnormality and CD4 count in HIV positive women was taken up in a Care and Support Hospital in collaboration with the Department of Pathology, Government Medical College, Ananthapuramu. Based on the observations, periodic cervical screening in HIV positive women is emphasized.

Results: 3.03% of women showed presence of cervical epithelial abnormality among HIV positive women. More number of HSIL (50%) followed by LSIL (28.2%), ASCUS (20.16%) and Carcinoma Cervix (1.6%).

Conclusion: Present study also emphasizes that patients with low CD4 count are at high risk of developing precancerous lesions of cervix. Hence periodic biannual cervical screening is required for HIV positive women whose CD4 count is below 200, to bring down the incidence of cervical malignancy and premalignant conditions.

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A study of CD4 count and cervical epithelial abnormality in HIV positive women
CITATION
DOI: 10.17511/ijmrr.2016.i07.13
Published: 2016-07-31
How to Cite
1.
KP V, Swapna RS, Sarma H, Monoranjan M, M N. A study of CD4 count and cervical epithelial abnormality in HIV positive women. Int J Med Res Rev [Internet]. 2016Jul.31 [cited 2024Mar.28];4(7):1144-7. Available from: https://ijmrr.medresearch.in/index.php/ijmrr/article/view/618
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Original Article