A rare case of gastric carcinoid presenting as subacute combined degeneration of spinal cord
Keywords:
Gastric carcinoid, Subacute combined degeneration, spinal cord
Abstract
Gastric carcinoids originate from the foregut and are derived from enterochromaffin-like (ECL) cells, which are the main neuroendocrine cells in the gastric mucosa. Gastrin acts directly on ECL cells to induce hyperplasia, dysplasia, and, eventually, neoplasia or carcinoid . In patients with chronic atrophic gastritis, decreased gastric acid secretion stimulates the secretion of gastrin, and ECL cells transform into a carcinoid. Herein we report a case of type I gastric carcinoid presenting as SACD.
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2. Granberg D, Wilander E, Stridsberg M, Granerus G, Skogseid B, Öberg K. Clinical symptoms, hormone profiles, treatment, and prognosis in patients with gastric carcinoids. Gut. 1998. 43. 223-228.
3. Fauci AS, Loscalzo J, Kasper DL, Hauser SL, Longo DL, Jameson JL, et al., editors. Harrison’s principles of internal medicine. 19th ed. New York: McGraw Hill. 2015.
4. Hwang JH, Rulyak SD, Kimmey MB. American Gastroenterological Association Institute. American Gastroenterological Association Institute technical review on the management of gastric subepithelial masses. Gastroenterology. 2006. 130. 2217–2228.
5. Modlin IM, Lye KD, Kidd M. A 5-decade analysis of 13,715 carcinoid tumors. Cancer.2003. 97. 934–959.
6. Hung OY, Maithel SK, Willingham FF, Farris III AB, Kauh JS. Hypergastrinemia, Type 1 Gastric Carcinoid Tumors: Diagnosis and Management. Journal of American Society of Clinical Oncology. 2015. 29. e713-e715.
7. Singh NN, Thomas FP. Vitamin B-12 Associated Neurological Diseases [Internet].2015 Nov 23. Available from Medscape: http://emedicine.medscape.com/article/1152670
8. Cameron K Tebbi. Carcinoid Tumor Treatment & Management.[Internet]. 2015 Jun 17. Available from Medscape: http://emedicine.medscape.com/article/986050
CITATION
DOI: 10.17511/ijmrr.2016.i05.21
Published: 2016-05-31
How to Cite
1.
Sharma A, Gowtham G, Nawal C, Agarwal M, Chejara R. A rare case of gastric carcinoid presenting as subacute combined degeneration of spinal cord. Int J Med Res Rev [Internet]. 2016May31 [cited 2024Dec.23];4(5):784-6. Available from: https://ijmrr.medresearch.in/index.php/ijmrr/article/view/570
Issue
Section
Case Report
OAI - Open Archives Initiative
