T-Cell Lymphoma of Oral Cavity: A Case Report
Keywords:
Extranodal, Non-Hodgkin’s lymphoma, Oral cavity, Soft palate, Hard palate
Abstract
Malignant lymphomas are heterogenous group of neoplasms of lymphoid tissues with different clinical courses and varied prognosis. Non-Hodgkin’s lymphoma (NHL) often presents at the extranodal sites of head and neck region, but the intraoral lesions are much less frequent, especially when they are the only manifestation of the disease. The oral cavity including the palate, gingiva, tongue, buccal mucosa, floor of the mouth and lips are the primary sites for approximately 2% of all extranodal lymphomas. We here report the case of a 40 years old male that had initial extra nodal intraoral presentations undiagnosed previously. The clinical, histopathological and immunological examinations revealed T-cell lymphoma.
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References
1. Vinoth PN, Selvan SM, Sahni L, Krishnaratnam K, Rajendiran S, Anand CV, Scott JX. Primary extra nodal non-Hodgkin's lymphoma of the oral cavity in a young girl. Natl J Maxillofac Surg. 2012 Jul;3(2):187-9. doi: 10.4103/0975-5950.111377. [PubMed]
2. Spatafore CM, Keyes G, Skidmore AE. Lymphoma: an unusual oral presentation. J Endod. 1989 Sep;15(9):438-41. [PubMed]
3. Ratech H, Burke JS, Blayney DW, Sheibani K, Rappaport H. A clinicopathologic study of malignant lymphomas of the nose, paranasal sinuses, and hard palate, including cases of lethal midline granuloma. Cancer. 1989 Dec 15;64(12):2525-31.
4. Yin HF, Jamlikhanova V, Okada N, Takagi M. Primary natural killer/T-cell lymphomas of the oral cavity are aggressive neoplasms. Virchows Arch. 1999 Oct;435(4):400-6. [PubMed]
5. Griffin TJ, Hurst PS, Swanson J. Non-Hodgkin's lymphoma: a case involving four third molar extraction sites. Oral Surg Oral Med Oral Pathol. 1988 Jun;65(6):671-4. [PubMed]
6. Kobler P, Borcic J, Filipovic ZI, Nola M, Sertic D. Primary non-Hodgkin's lymphoma of the oral cavity. Oral Oncology Extra. 2005;41:12–4.
7. Sargeant KP, Grider DJ, Eagan PA, Davey DD, Damm DD, Robinson RA, et al. Lymphomas of the oral soft tissues are not preferentially associated with latent or replicative Epstein-Barr virus. Gulley M.L; Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics ISSN 1079- 2104 Source / Source Congrès American Academy of Oral Medicine. Annual meeting. 1995;80:420–31.
8. Gedik R, Gedik S, Göze F, Develioglu H. Lymphoma in the infraorbital region. J Am Dent Assoc. 2003 Oct;134(10):1353-5. [PubMed]
9. Urquhart A, Berg R. Hodgkin's and non-Hodgkin's lymphoma of the head and neck. Laryngoscope. 2001 Sep;111(9):1565-9. [PubMed]
10. van der Waal RI, Huijgens PC, van der Valk P, van der Waal I. Characteristics of 40 primary extranodal non-Hodgkin lymphomas of the oral cavity in perspective of the new WHO classification and the International Prognostic Index. Int J Oral Maxillofac Surg. 2005 Jun;34(4):391-5.
11. Maheshwari GK, Baboo HA, Gopal U, Wadhwa MK. Primary extra-nodal non-Hodgkin's lymphoma of the cheek. J Postgrad Med. 2000 Jul-Sep;46(3):211-2. [PubMed]
12. Pazoki A, Jansisyanont P, Ord RA. Primary non-Hodgkin's lymphoma of the jaws: Report of 4 cases and review of the literature. J Oral Maxillofac Surg. 2003 Jan;61(1):112-7. [PubMed]
13. Jayakrishnan R, Thomas G, Kumar A, Nair R. Non-Hodgkin's lymphoma of the hard palate. J Oral MaxillofacPathol. 2008;12:85–7. [PubMed]
14. Margiotta V, Franco V, Rozzo A, Porter S, et al. Gastric and gingival localization of mucosa-associated lymphoid tissue (MALT) lymphoma. An Immuno-histochemical, virological and clinical case report. J. Periodontol., 70 (1999), pp. 914–918.
15. Koga M, Kusukawa J, Hayabuchi N. Spontaneous regression of extranodal malignant lymphoma occurred in the gingiva. Oral Oncol. 2003 Apr;39(3):323-4.
16. Enrique A, Quesada JL, Lorente J, López D. [Hodgkin and Non-Hodgkin lymphomas in otorhinolaryngology]. Acta Otorrinolaringol Esp. 2004 Oct;55(8):387-9. [PubMed]
17. Angiero F, Stefani M, Crippa R. Primary non-Hodgkin's lymphoma of the mandibular gingiva with maxillary gingival recurrence. Oral Oncol Extra. 2006;42:123–8. [PubMed]
18. Ferlay J, Bray F, Pisani P, Parkin DM. 2001. Lyon: IARC; GLOBOCAN 2000: cancer incidence, mortality and prevalence worldwide, version 1.0 IARC cancer Base No. 5, Lyon: IARC, 2001.
19. Harris NL, Jaffe ES, Stein H, Banks PM, Chan JK, Cleary ML, et al. A revised European American classification of lymphoid neoplasms: A proposal from the international study lymphoma group. Blood. 1994;84:1361–92.
20. Harris NL, Jaffe ES, Stein H, Vardiman JW. World Health Organisation Classification of Tumours. Pathology and genetics of tumours of the haemopoetic and lymphoid tissues. Lyon: IARC press; 2001.
21. Carbone PP, Kaplan HS, Musshoff K, Smithers DW, Tubiana M. Report of the Committee on Hodgkin's Disease Staging Classification. Cancer Res. 1971 Nov;31(11):1860-1. [PubMed]
22. Rooney N, Ramsay AD. Lymphomas of the head and neck. 2; The B-cell lymphomas. Eur J Cancer B Oral Oncol. 1994 May;30B(3):155-9.
2. Spatafore CM, Keyes G, Skidmore AE. Lymphoma: an unusual oral presentation. J Endod. 1989 Sep;15(9):438-41. [PubMed]
3. Ratech H, Burke JS, Blayney DW, Sheibani K, Rappaport H. A clinicopathologic study of malignant lymphomas of the nose, paranasal sinuses, and hard palate, including cases of lethal midline granuloma. Cancer. 1989 Dec 15;64(12):2525-31.
4. Yin HF, Jamlikhanova V, Okada N, Takagi M. Primary natural killer/T-cell lymphomas of the oral cavity are aggressive neoplasms. Virchows Arch. 1999 Oct;435(4):400-6. [PubMed]
5. Griffin TJ, Hurst PS, Swanson J. Non-Hodgkin's lymphoma: a case involving four third molar extraction sites. Oral Surg Oral Med Oral Pathol. 1988 Jun;65(6):671-4. [PubMed]
6. Kobler P, Borcic J, Filipovic ZI, Nola M, Sertic D. Primary non-Hodgkin's lymphoma of the oral cavity. Oral Oncology Extra. 2005;41:12–4.
7. Sargeant KP, Grider DJ, Eagan PA, Davey DD, Damm DD, Robinson RA, et al. Lymphomas of the oral soft tissues are not preferentially associated with latent or replicative Epstein-Barr virus. Gulley M.L; Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics ISSN 1079- 2104 Source / Source Congrès American Academy of Oral Medicine. Annual meeting. 1995;80:420–31.
8. Gedik R, Gedik S, Göze F, Develioglu H. Lymphoma in the infraorbital region. J Am Dent Assoc. 2003 Oct;134(10):1353-5. [PubMed]
9. Urquhart A, Berg R. Hodgkin's and non-Hodgkin's lymphoma of the head and neck. Laryngoscope. 2001 Sep;111(9):1565-9. [PubMed]
10. van der Waal RI, Huijgens PC, van der Valk P, van der Waal I. Characteristics of 40 primary extranodal non-Hodgkin lymphomas of the oral cavity in perspective of the new WHO classification and the International Prognostic Index. Int J Oral Maxillofac Surg. 2005 Jun;34(4):391-5.
11. Maheshwari GK, Baboo HA, Gopal U, Wadhwa MK. Primary extra-nodal non-Hodgkin's lymphoma of the cheek. J Postgrad Med. 2000 Jul-Sep;46(3):211-2. [PubMed]
12. Pazoki A, Jansisyanont P, Ord RA. Primary non-Hodgkin's lymphoma of the jaws: Report of 4 cases and review of the literature. J Oral Maxillofac Surg. 2003 Jan;61(1):112-7. [PubMed]
13. Jayakrishnan R, Thomas G, Kumar A, Nair R. Non-Hodgkin's lymphoma of the hard palate. J Oral MaxillofacPathol. 2008;12:85–7. [PubMed]
14. Margiotta V, Franco V, Rozzo A, Porter S, et al. Gastric and gingival localization of mucosa-associated lymphoid tissue (MALT) lymphoma. An Immuno-histochemical, virological and clinical case report. J. Periodontol., 70 (1999), pp. 914–918.
15. Koga M, Kusukawa J, Hayabuchi N. Spontaneous regression of extranodal malignant lymphoma occurred in the gingiva. Oral Oncol. 2003 Apr;39(3):323-4.
16. Enrique A, Quesada JL, Lorente J, López D. [Hodgkin and Non-Hodgkin lymphomas in otorhinolaryngology]. Acta Otorrinolaringol Esp. 2004 Oct;55(8):387-9. [PubMed]
17. Angiero F, Stefani M, Crippa R. Primary non-Hodgkin's lymphoma of the mandibular gingiva with maxillary gingival recurrence. Oral Oncol Extra. 2006;42:123–8. [PubMed]
18. Ferlay J, Bray F, Pisani P, Parkin DM. 2001. Lyon: IARC; GLOBOCAN 2000: cancer incidence, mortality and prevalence worldwide, version 1.0 IARC cancer Base No. 5, Lyon: IARC, 2001.
19. Harris NL, Jaffe ES, Stein H, Banks PM, Chan JK, Cleary ML, et al. A revised European American classification of lymphoid neoplasms: A proposal from the international study lymphoma group. Blood. 1994;84:1361–92.
20. Harris NL, Jaffe ES, Stein H, Vardiman JW. World Health Organisation Classification of Tumours. Pathology and genetics of tumours of the haemopoetic and lymphoid tissues. Lyon: IARC press; 2001.
21. Carbone PP, Kaplan HS, Musshoff K, Smithers DW, Tubiana M. Report of the Committee on Hodgkin's Disease Staging Classification. Cancer Res. 1971 Nov;31(11):1860-1. [PubMed]
22. Rooney N, Ramsay AD. Lymphomas of the head and neck. 2; The B-cell lymphomas. Eur J Cancer B Oral Oncol. 1994 May;30B(3):155-9.
CITATION
DOI: 10.17511/ijmrr.2016.i03.20
Published: 2016-03-30
How to Cite
1.
Prashant D, Saify F, Tiwari N, Viplav P. T-Cell Lymphoma of Oral Cavity: A Case Report. Int J Med Res Rev [Internet]. 2016Mar.30 [cited 2024Dec.23];4(3):397-00. Available from: https://ijmrr.medresearch.in/index.php/ijmrr/article/view/501
Issue
Section
Case Report
OAI - Open Archives Initiative
