Study of Jaundice profile in Pregnancy in tertiary care centre in central India
Abstract
Introduction: Pregnancy is complicated by various disorders including jaundice which is an important medical disorder seen more often in developing countries. Jaundice complicates pregnancy, whether of any cause. Jaundice in pregnancy carries a grave prognosis for both the foetus as well as mother. Therefore early detection of cause of jaundice improves the outcome of both.
Methods: In present study 50 cases of clinical jaundice with pregnancy in any trimester were selected in the age group of 20 to 35 years over a period of one year.
Results: Viral hepatitis was observed in 38 (76%) cases, intrahepatic Cholestasis of pregnancy in 7 (14%) cases, HELLP and hyperemesis gravidarum in 2 (4%) cases each and a single case of drug induced jaundice. Maximum cases of jaundice in pregnancy were observed among the age group between 20 -25 years.
Conclusion: Viral hepatitis was seen as the commonest cause of jaundice dominating in all the three trimesters, third trimester having maximum 32 (64%) cases. Therefore monitoring and early diagnosis of jaundice is necessary during pregnancy.
Downloads
References
2. Dhawan PS, Sainani GS. Diagnosis of liver disorder in pregnancy. Am J Obstetrics & Gynaecology. 1996; 23: 609-13.
3. Kaczynski K, Kamili S. Global epidemiology and Medical aspect of hepatitis E. Forum (Geneva). 2001; (2):166-179. [PubMed]
4. Nagaria T, Agarwal S. Fetomaternal outcome in jaundice during pregnancy. J Obstet Gynecol India. 2005;55:424–427.
5. Mitra AK, Patki PS, Mitra SK. Liver disorders during pregnancy and their management. The Antiseptic. 2008; 105 (4): 193-196.
6. Wolf JL. Liver disease in pregnancy. Med Clinics of North Am. 1996; 80:1167-1187. [PubMed]
7. Sookoian S. Liver disease during pregnancy: acute viral hepatitis. Annals of Hepatology. 2006; 5(3): 231-236.
8. Jan Y, Bilques S, Najmi AM, Qureshi MA, Khan SS, Rafiq M, Ashfaq A. Viral Hepatitis during Pregnancy: A Study of Its Socio- Clinical Profile in A Tertiary Care Hospital. J Dental and Med Sci. 2012 Dec; 3(2):18-22.
9. Shukla S, Mehta G, Jais M, Singh A. A Prospective Study on Acute Viral Hepatitis in Pregnancy; Seroprevalence and Fetomaternal Outcome of 100 cases. J Biosci Tech. 2011; 2 (3): 279-286.
10. Lahiri BC. Jaundice in pregnancy. J Obstet Gynaecol India. 1976; 26: 363-67.
11. Ching LY, Barge N, Dalal AR. Study of jaundice in a tertiary care institution in India. Bombay Hospital J. 2011; 53: 181-183.
12. Ch’ng CL, Morgan M, Hainsworth I, Kingham JGC. Prospective study of liver dysfunction in pregnancy in Southwest Wales. Gut. 2002; 51: 876–880.
13. Abell TL, Riely CA. Hyperemesis gravidarum. Gastroentrol Clinic North Am. 1992; 21: 835. [PubMed]
14. Jaiswal SP, Jain AK, Naik G, Soni N, Chitnis DS. Viral hepatitis during pregnancy. Int J Gynaecol Obstet. 2001; 72: 103-8. [PubMed]
15. Singh S, Mohanty A, Joshi YK, Deka D, Mohanty S, Panda SK. Mother-to-child transmission of hepatitis E virus infection. Indian J Pediatr. 2003 Jan; 70(1): 37-39.