Spectrum of male breast lesions: an institutional perspective

  • Dr Siyum Ganguly Demonstrator, Department of Pathology, Silchar Medical College and Hospital, Silchar, Assam, India
  • Dr Shah Alam Sheikh Associate Professor, Department of Pathology, Silchar Medical College and Hospital, Silchar, Assam, India
  • Dr Angela Phukan Postgraduate student, Department of Pathology, Silchar Medical College and Hospital, Silchar, Assam, India
  • Dr Jahnabi Das Postgraduate student, Department of Pathology, Silchar Medical College and Hospital, Silchar, Assam, India
  • Dr Surjya Sekhar Das Postgraduate student, Department of Pathology, Silchar Medical College and Hospital, Silchar, Assam, India
DOI: https://doi.org/10.17511/ijmrr.2016.i03.17
Keywords: FNAC, Gynecomastia, Infiltrating duct carcinoma, Male breast lesions

Abstract

Background: Fine needle aspiration is a quick and effective method in the diagnosis of breast lumps and is being widely used in the preoperative assessment of breast lesions. Studies related to male breast lesions are rare. The aim of our study is to study the spectrum of male breast lesions and to analyze the cytological spectrums of these lesions.

Materials and Methods: The study was conducted over a period of 5 years. FNAC was done on all male patients clinically presenting with breast lesions. Cytological findings were retrospectively correlated with histopathological dignosis. FNAC diagnosis was categorized as benign, malignant, suspicious of malignancy and unsatisfactory.

Results: Male breast lesions formed 6.2% (38 cases) of the 612 breast lesions which were sent for FNA over a period of 5 years. Of these histopathological examination was done only in 19 cases. 86.8% (33 cases) were benign or reactive and 10.6% (4 cases) were malignant. Gynecomastia was the commonest benign lesion (29 cases).

Conclusion: This study showed that FNAC is a reliable, sensitive and specific diagnostic tool for diagnosing male breast lesions. Hence, it should be used as a first line of investigation in the evaluation of male breast lesions.

Downloads

Download data is not yet available.

References

1. Gupta RK, Naran S, Dowle CS, Simpson JS. The diagnostic impact of needle aspiration cytology of the breast on clinical decision making with an emphasis on the aspiration cytodiagnosis of male breast masses. Diagn Cytopathol 1991; 7(6):637-9. DOI: 10.1002/dc.2840070620.

2. Eisenberg AJ, Hajdu SI, Wilhelmus J, Melamed MR, Kinne D. Preoperative aspiration cytology of breast tumors. Acta Cytol. 1986 Mar-Apr; 30(2):135-46. [PubMed]

3. Siddiqui MT, Zakowski MF, Ashfaq R, Ali SZ: Breast masses in males: multi-instituitional experience on fine needle aspiration. Diag Cytopathology.2002 Feb;26(2): 87-91. [PubMed]

4. Nuttal FQ. Gynecomastia as a physical finding in normal men. J Clin Endocrinol Metab 1979 Feb;48(2):338–340. doi: 10.1210/jcem-48-2-338. [PubMed]

5. Das DK, Junaid TA, Mathews SB, Ajrawi TG, Ahmed MS, Madda JP. Fine needle aspiration cytology diagnosis of male breast lesions: A study of 185 cases. Acta Cytol 1995 Sep-Oct;39(5):870–876. [PubMed]

6. Rosen DG, Laucirica R, Verstovsek G. Fine needle aspiration of male breast lesions. Acta Cytol. 2009 Jul-Aug; 53(4):369-74. [PubMed]

7. Silverman JF, Lannin DR, O’Brien K, Norris HT. The triage role of fine needle aspiration biopsy of palpable breast masses- diagnostic accuracy and cost-effectiveness. Acta Cytol. 1987 Nov-Dec; 31(6):731-36. [PubMed]

8. Palombini L, Fulciniti F, Vetrani A, et al. Fine needle aspiration biopsies of Breast masses – A critical analysis of 1956 cases in 8 years. Cancer. 1988 Jun 1; 61(11):2273-7.

9. Lilleng R, Paksoy N, Vural G, Langmark F, Hagmar B. Assesment of fine needle aspiration cytology and histopathology for diagnosing male breast masses. Acta Cytol. 1995 Sep-Oct; 39(5):877-81. [PubMed]

10. Feichter GE, Haberthur F, Gobat S, Dalquen P. Breast cytology- statistical analysis and cytohistologic correlations. Acta Cytol. 1997 Mar-Apr; 41(2):327-32. [PubMed]

11. Joshi A, Kapila K, Verma K. Fine needle aspiration cytology in the management of male breast masses. Nineteen years of experience. Acta Cytol. 1999 May-Jun;43(3):334-38. [PubMed]

12. Bhat N, Rosato EF, Gupta PK. Gynecomastia in a Mortician. Acta Cytol. 1990 Jan- Feb;34(1):31-34. [PubMed]

13. Amrikachi M, Green LK, Rone R, Ramzy I. Gynecomastia- cytologic features and diagnostic pitfalls in fine needle aspirates. Acta Cytol. 2001 Nov- Dec;45(6):948-52. [PubMed]

14. Rai B, Ghoshal S, Sharma SC. Breast cancer in males: A PGIMER experience. J Can Res Ther. 2005 Jan- Mar;1(1):31-33. [PubMed]

15. Amrikachi M, Green LK, Rone R, Ramzy I. Gynecomastia: Cytologic features and diagnostic pitfalls in fine needle aspirates. Acta Cytol. 2001 Nov- Dec;45(6):948-52. [PubMed]

16. Coghill S, Howat A. Inflammatory conditions and benign breast lesions. In: Diagnostic Cytopathology. Gray W, McKee GT. Elsevier 2004. 2nd edn. Pg 257- 78. [PubMed]

17. Silverman JF, Saad RS. Breast. In: Comprehensive Cytopathology. Bibbo M, Wilbur D. Elsevier 2008. 3rd edn. P. 713-772.

18. Lilleng R, Paksoy N, Vural G, Langmark F, Hagmar B. Assessment of fine needle aspiration cytology and histopathology for diagnosing male breast masses. Acta Cytol 1995 Sep- Oct;39(5):877–881. [PubMed]

19. Martin-Bates E, Krausz T, Phillips I: Evaluation of fine needle aspiration of the male breast for the diagnosis of gynecomastia. Cytopathol. 1990;1 (2):79-85. [PubMed]

20. Russin VL, Lachowicz C, Kline TS. Male breast lesions: gynecomastia and its distinction from carcinoma by aspiration biopsy cytology. Diagn Cytopathol. 1989;5(3):243-47.

21. Heller KS, Rosen PP, Schottenfeld D, Ashikari R, Kinne DW. Male breast cancer: A clinicopathologic study of 97 cases. Ann Surg 1978 Jul;188(1):60–65. [PubMed]

22. Wilson JD, Aiman J, Mac Donald PC. The pathogenesis of gynecomastia. Adv Intern Med 1980;25:1–32. [PubMed]

23. Ersek RA, Schaeferle M, Beckham P. Gynecomastia: Aesthet Surg J 2000 Sep(5):381–86.

24. MacIntosh RF, Merrimen JL, Barnes PJ. Application of the probabilistic approach to reporting breast fine needle aspiration in males. Acta Cytol. 2008 Sep- Oct;52(5):530-34. [PubMed]

25. Westend PJ, Jobse C. Evaluation of fine-needle aspiration cytology of breast masses in males. Cancer. 2002 April 25;96(2):101-04. [PubMed]

26. Wauters CA, Kooistra BW, Heijden IMK, Strobbe LJ. Is cytology useful in the diagnostic workup of male breast lesions? A retrospective study over a 16-year period and review of the recent literature. Acta Cytol. 2010 May- Jun; 54(3):259-64.
Spectrum of male breast lesions: an institutional perspective
CITATION
DOI: 10.17511/ijmrr.2016.i03.17
Published: 2016-03-31
How to Cite
1.
Ganguly S, Sheikh SA, Phukan A, Das J, Das SS. Spectrum of male breast lesions: an institutional perspective. Int J Med Res Rev [Internet]. 2016Mar.31 [cited 2024Apr.20];4(3):381-6. Available from: https://ijmrr.medresearch.in/index.php/ijmrr/article/view/489
Issue
Vol 4 No 3 (2016): MARCH
Section
Original Article