To study the prevalence of tuberculosis in children of sputum positive adult of pulmonary tuberculosis living in same household

  • Dr P. Beck Associate Professor, Pt JNM Medical College, Raipur, CG, India
  • Dr Virendra K. Kurrey Associate Professor, Pt JNM Medical College, Raipur, CG, India
  • Dr Prafull Dawale Associate Professor, Government Medical College Rajnandgaon, CG, India
Keywords: Childhood Tuberculosis, Extrapulmonary Tuberculosis, RNTCP, Antitubercular drugs

Abstract

Introduction: Mortality due to tuberculosis can be prevented with proper screening, diagnosis and treatment. Present study is proposed to propagate screening of all children in families of all adult with sputum positive for AFB by relevant test available locally. This will help in early detection childhood infection. Objective of this study was to identify the prevalence of tuberculosis in children of sputum positive adult of pulmonary tuberculosis living in same household. If the findings are statistically significant routine screening should be recommended as part of RNTCP.

Method: Prospective, hospital plus community based study during a period of February 20013 to November 20014, inclusion criteria includes all children 5-14 year, should have contact with sputum positive adult, exclusion criteria - children who treated with antitubercular, TB with concurrent immunosupression, Detail history, clinical examination, and investigation done to find out tubercular infection or disease.

Result: We observed that among 218 children 40% children had tubercular infection out of which 23 children had tubercular disease. Data of different parameter is observed and analyzed which is found statistically significant.

Conclusion: This study argue strongly in favours of routine screening of all children in contact with sputum positive adult of PTB and identify this group of child at high risk who should be screened on a priority basis if there of resources and time to screen all family contact.

Downloads

Download data is not yet available.

References

1. Rieder HL. Contacts of tuberculosis patients in high-incidence countries. Int J Tuberc Lung Dis. 2003 Dec;7(12 Suppl 3):S333-6. [PubMed]

2. Donald PR, Marais BJ, Barry CE 3rd. Age and the epidemiology and pathogenesis of tuberculosis. Lancet. 2010 May 29;375(9729):1852-4. doi: 10.1016/S0140-6736(10)60580-6. Epub 2010 May 18. [PubMed]

3. Centers for Disease Control and Prevention. Estimates for future global tuberculosis and mortality. JAMA. 1994 Mar 9;271(10):739, 741. [PubMed]

4. Charnace G de, Delacourt C. Diagnostic techniques in paediatric tuberculosis. Paediatr Respir Rev. 2001 Jun;2(2):120-6. [PubMed]

5. World Health Organization. Global Tuberculosis Report. Geneva: World Health Organization; 2013. Available at: http://www.who.int/tb/publications/global_report/en/index.html.

6. WHO Global tuberculosis report, http://www.who.int/tb/publications/global_report/gtbr13_executive_summary.pdf.

7. World Health Organization. (2010). The global plan to stop TB 2011-2015: transforming the fight towards elimination of tuberculosis.

8. Bairwa M, Rajput M, Sachdeva S. Modified kuppuswamy’s socioeconomic scale: social researcher should include updated income criteria, 2012 Indian J Community Med. 2013 Jul-Sep; 38(3): 185–186. doi: 10.4103/0970-0218.116358.

9 Fox GJ, Dobler CC, Marks GB. Active case finding in contacts of people with tuberculosis. Cochrane Database Syst Rev. 2011 Sep 7;(9):CD008477. doi: 10.1002/14651858.CD008477.pub2. [PubMed]

10. Altet MN, Alcaide J, Plans P et al. Passive smoking and the risk of pulmonary tuberculosis in children immediately following infection. A case control study. Tuber Lung Dis. 1996 Dec;77(6):537-44. [PubMed]

11. Newton SM, Brent AJ, Anderson S, et al. Paediatric tuberculosis. Lancet Infect Dis. 2008 Aug;8(8):498-510. doi: 10.1016/S1473-3099(08)70182-8. [PubMed]

12. Stop TB Partnership Childhood TB Subgroup, World Health Organization. Guidance for National Tuberculosis Programmes on the management of tuberculosis in children. Int J Tuberc Lung Dis. 2006 Nov;10(11):1205-11.

13. Salazar-Vergara RM, Sia IG, Tupasi TE, et al. Tuberculosis infection and disease in children living in households of Filipino patients with tuberculosis: a preliminary report. Int J Tuberc Lung Dis 2003;7(12 Suppl. 3):S494–500. [PubMed]

14. Vallejo JG, Ong LT, Starke JR. Clinical features, diagnosis, and treatment of tuberculosis in infants. Pediatrics. 1994 Jul;94(1):1-7. [PubMed]

15. Singh M, Mynak ML, Kumar L, et al. Prevalence and risk factors for transmission of infection among children in household contact with adults having pulmonary tuberculosis. Arch Dis Child. 2005 Jun;90(6):624-8. [PubMed]

16. Schoeman JH,Westaway MS, Neethling A. The realationship between socioeconomic factors and pulmonary tuberculosis. Int J Epidemiol. 1991 Jun;20(2):435-40. [PubMed]

17. Jaganath D, Mupere E. Childhood tuberculosis and malnutrition. J Infect Dis. 2012;206(12):1809–1815. [PubMed]

18. Kumar, RA, Saran, M, Verma, BL, Srivastava, RN. Pulmonary tuberculosis among contacts of patients with tuberculosis in an urban Indian population. J Epidemiol Community Health. 1984 Sep;38(3):253-8.

19. Bhakoo, ON, Gupte SP. Tuberculosis in children. Indian J Pediatr. 1969 Mar;36(254):65-70. [PubMed]

20. Caldeira, Zelina MR, Clemax C. Sant'Anna, and Miguel Abdom Aidé. Tuberculosis contact tracing among children and adolescents, Brazil. Paediatr Respir Rev. 2001 Jun;2(2):120-6.

21. Fuimaono A, Vince J. Screening contacts of children with tuberculosis: an important and worthwhile part of case management. P N G Med J. 1997 Jun;40(2):69-73. [PubMed]

22. Lifschitz, Martin. The value of the tuberculin skin test as a screening test for tuberculosis among BCG-vaccinated children. Pediatrics. 1965 Oct;36(4):624-7.
CITATION
DOI: 10.17511/ijmrr.2015.i6.118
Published: 2015-07-31
How to Cite
1.
Beck P, K. Kurrey V, Dawale P. To study the prevalence of tuberculosis in children of sputum positive adult of pulmonary tuberculosis living in same household. Int J Med Res Rev [Internet]. 2015Jul.31 [cited 2024Nov.22];3(6):608-13. Available from: https://ijmrr.medresearch.in/index.php/ijmrr/article/view/289
Section
Original Article