Predictor of neonatal morbidity in birth asphyxia
Keywords:
birth asphyxia, Neonatal morbidity, Predictor of outcome
Abstract
Hypoxic ischaemic brain damage is a major cause of neonatal mortality and morbidity. Similar degrees of insult may completely spare one child and devastate another, so very sensitive prognostic parameters are needed. Conventional predictors like fetal heart rate patterns, Apgar scores, need for resuscitation and umbilical arterial blood gas analysis show variable predictive values of outcome in neonates with asphyxia.
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References
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2. Da Silva S, Hennebert N, Denis R, Wayenberg J-L. Clinical value of a single postnatal lactatemeasurement after intrapartum asphyxia. Acta Pædiatr 2000; 89(3): 320–3. 10.1111/j.1651-2227.2000.tb01334.x
3. Mathias Karlsson, Eva Wiberg‐Itzel, Ela Chakkarapani, Mats Blennow, Birger Winbladh, Marianne Thoresen. Lactate dehydrogenase predicts hypoxic ischaemic encephalopathy in newborn infants: a preliminary study. Acta Paediatrica 2010;99(8) : 1139–1144. Doi: 10.1111/j.1651-2227.2010.01802.x
4. Martha Douglas-Escobar, Michael D. Weiss. Neonatal Biomarkers of Brain Injury; NeoReviews Vol.14 No.10 October 2013 e501. doi: 10.1542/neo.14-10-e501.
5. Gazzolo D, Frigiola A, Bashir M, et al. Diagnostic accuracy of S100b urinary testing at birth in full-term asphyxiated newborns to predict neonatal death. PloS one. 2009;Feb 4(2):e4298 doi: 10.1371/journal.pone.0004298. [PubMed]
6. Qian J, Zhou D, Wang YW. Umbilical artery blood S100b protein: a tool for the early identification of neonatal hypoxicischemic encephalopathy. Eur J Pediatr. 2009;168(1):71–77. . doi: 10.3389/fneur.2012.00144 PMCID: PMC3486976. [PubMed]
7. E Thornberg, K Thiringer, H Hagberg, I Kjellmer.Neuron specific enolase in asphyxiated newborns: association with encephalopathy and cerebral function monitor trace. Arch Dis Child Fetal Neonatal Ed. 1995 Jan; 72(1): F39–F42.
8. Tu¨rker G, Babaog˘lu K, Go¨kalp AS, Sarper N, Zengin E, Arisoy AE. Cord blood cardiac Troponin I as an early predictor of short-term outcome in perinatal hypoxia. Biol Neonate 2004; 86: 131–7.
9. Pal P, Goel M. ECG changes in birth asphyxia and its correlation with Cardiac troponin-I. Int J Med Res Rev 2015;3(4):400-403. doi: 10.17511/ijmrr.2015.i4.075.
CITATION
DOI: 10.17511/ijmrr.2015.i4.085
Published: 2015-05-31
How to Cite
1.
Chandran R, Gedam DS. Predictor of neonatal morbidity in birth asphyxia. Int J Med Res Rev [Internet]. 2015May31 [cited 2024Nov.8];3(4):364-5. Available from: https://ijmrr.medresearch.in/index.php/ijmrr/article/view/242
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Editorial
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