Visual evoked Potential (VEP): Physiological variation in normal children and adolescent up to 20 years of age

  • Dr Jyoti Wadhera Assistant Professor, Department of Physiology, KD Medical College Hospital and Research Center, Mathura, UP, India
  • Dr Vandana Dudhmal Associate Professor, Department of Physiology, KD Medical College Hospital and Research Center, Mathura, UP, India
Keywords: Visual evoked Potential, N70 latency in children, P100 amplitude in children

Abstract

Introduction: Visual evoked Potential is the electrical potential difference recorded from the surface of scalp in response to Visual stimuli. It represents a resultant response of cortical as well as subcortical areas to photostimulation. Although various studies have been done on visual evoked potential but there are few studies from India only. Therefore this study was planned to study visual evoked potentials by recording battery of N70, P100 & N155 waveform in different age groups of normal healthy children.

Methods: Present study was conducted in department of Physiology of Tertiary care teaching hospital. 50 healthy patients were included in two groups, below 5 years and 6- 20 years. Visual evoked Potential has been recorded and their physiological Variation has been observed.

Results: It was seen that mean value and standard deviation of amplitude of N70 wave in left eye showed significant decrease in age group of 4 to 5 years. Mean value and standard deviation of amplitude of P 100 wave in right eye showed significant decrease in age group of 4 to 5 years. Other values were not significant.

Conclusion: Age and sex have little impact on Visual evoked Potential in children. Eye dominance has been observed more commonly.

Downloads

Download data is not yet available.

References

1. Misra UK, Kalita J. visual evoked Potential- Anatomical basis of visual evoked Potential. Clinical Neurophysiology, 1st edition, New Delhi: Elsevier,1998;250-251.

2. Martinović Z, Ristanović D, Jovanović V. Some uses of visual evoked potentials in the diagnostics of neurological disorders in developmental period. Neurologija. 1989;38(4):295-310.

3. Sircar S, Gautam S. Post-task changes in visual P300 and their reversibility through brief hyperventilation. Indian J Physiol Pharmacol. 2005 Apr;49(2):220-6.

4. Jain AK, Editor. Neuro- electrodiadnostic techniques. visual evoked potentials.In : Manual of Practical Physiology.1st Edition,Arya Publication, New Delhi;2003.p.261-2.

5. Adrian ED, Matthews R .The action of light on the eye: Part II. The processes involved in retinal excitation. J Physiol. 1927 Dec 29;64(3):279-301.

6. Misra UK, Kalita J. visual evoked Potential- Anatomical basis of visual evoked Potential. Clinical Neurophysiology, 1st edition, New Delhi: Elsevier,1998;p.311-324.

7. Stockard JE, Stockard JJ, Westmoreland BF, Corfits JL. Brainstem auditory-evoked responses. Normal variation as a function of stimulus and subject characteristics.. Arch Neurol. 1979 Dec;36(13):823-31.

8. Carrillo-de-la-Peña M1, Rodríguez Holguín S, Corral M, Cadaveira F. The effects of stimulus intensity and age on visual-evoked potentials (VEPs) in normal children. Psychophysiology. 1999 Nov;36(6):693-8.

9. Tandon OP, Ram D. Visual evoked responses to pattern reversal in children. Indian J Physiol Pharmacol. 1991 Jul;35(3):175-9.

10. Mukartihal GB, Radhakrishnan S, Reddy M, Ayyar SSK. Design and development of visual evoked potentials recording system for diagnosis of optic nerve diseases. J Instrum soc India 2006;36(4):227-34

11. Tondan OP, Average evoked potentials--clinical applications of short latency responses. Indian J Physiol Pharmacol. 1998 Apr;42(2):172-88. Review.

12. Fenwick PB, Brown D, Hennesey J. The visual evoked response to pattern reversal in 'normal' 6-11-year-old children. Electroencephalogr Clin Neurophysiol. 1981 Jan;51(1):49-62.

13. Lenassi E, Likar K, Stirn-Kranjc B, Brecelj J. VEP maturation and visual acuity in infants and preschool children. Doc Ophthalmol. 2008 Sep;117(2):111-20. doi: 10.1007/s10633-007-9111-8. Epub 2008 Jan 31.
CITATION
DOI: 10.17511/ijmrr.2015.i3.067
Published: 2015-04-30
How to Cite
1.
Wadhera J, Dudhmal V. Visual evoked Potential (VEP): Physiological variation in normal children and adolescent up to 20 years of age. Int J Med Res Rev [Internet]. 2015Apr.30 [cited 2024Dec.23];3(3):335-40. Available from: https://ijmrr.medresearch.in/index.php/ijmrr/article/view/235
Section
Original Article