Total colectomy of patients having synchronous lessons of five cases in Sylhet MAG Osmani Medical College, Bangladesh
Abstract
Background: Synchronous colorectal lesions present unique challenges in diagnosis and treatment, particularly in resource-limited settings. This study aims to evaluate the outcomes of total colectomy for synchronous colorectal lesions in a regional medical center in Bangladesh.
Methods: A retrospective case series of five patients who underwent total colectomy for synchronous colorectal lesions at Sylhet MAG Osmani Medical College Hospital between January 2019 and December 2023 was conducted. Patient demographics, clinical presentation, operative details, histopathological findings, and short-term outcomes were analyzed.
Results: The median age was 62 years (range: 48-75), with a male-to-female ratio of 3:2. The median number of synchronous lesions was 3 (range: 2-5). Three patients underwent open surgery, while two had laparoscopic-assisted procedures. The median operative time was 285 minutes (range: 240-360), with a median estimated blood loss of 350 mL (range: 200-600). Histopathology revealed adenocarcinoma in at least one lesion in three patients. The median length of hospital stay was 10 days (range: 8-15). Postoperative complications included ileus (n=2) and wound infection (n=1). No mortality or anastomotic leaks were observed within 30 days postoperatively. At 30-day follow-up, all patients reported satisfactory bowel function with a median stool frequency of 4 times per day.
Conclusion: Total colectomy for synchronous colorectal lesions can be safely performed with acceptable short-term outcomes in a regional medical center in Bangladesh. However, challenges remain in terms of resource availability and long-term follow-up. Further research is needed to optimize patient selection and perioperative management in resource-constrained settings.
Downloads
References
Rahman MS, et al. Incidence of colorectal cancer in Bangladesh: A population-based study. Asian Pac J Cancer Prev. 2021;22(3):897-902.
Smith JC, et al. Management of synchronous colorectal cancers: A systematic review and meta-analysis. Ann Surg Oncol. 2020;27(12):4631-4641.
Johnson PM, et al. Quality of life after total colectomy with ileorectal anastomosis: A systematic review. Dis Colon Rectum. 2019;62(8):982-992.
Chen HS, et al. Synchronous colorectal cancer: Clinical implications and treatment strategies. World J Gastroenterol. 2022;28(11):1232-1245.
Lee BC, et al. Characteristics of synchronous colorectal neoplasms detected in patients with colorectal cancer. Asian J Surg. 2018;41(6):528-533.
Lam AK, et al. Synchronous colorectal cancer: Clinical, pathological and molecular implications. World J Gastroenterol. 2014;20(22):6815-6820.
Ojo OS, et al. Synchronous colorectal carcinoma: A 10-year experience in a tertiary centre. J Gastrointest Cancer. 2019;50(3):532-536.
Latournerie M, et al. Epidemiology and prognosis of synchronous colorectal cancers. Br J Surg. 2008;95(12):1528-1533.
Parry S, et al. Metachronous colorectal cancer risk for mismatch repair gene mutation carriers: The advantage of more extensive colon surgery. Gut. 2011;60(7):950-957.
Aster VV, et al. Outcomes of total colectomy with ileorectal anastomosis for synchronous colorectal cancer. Int J Colorectal Dis. 2021;36(3):537-545.
Delaney CP, et al. Prospective, randomized, controlled trial between a pathway of controlled rehabilitation with early ambulation and diet and traditional postoperative care after laparotomy and intestinal resection. Dis Colon Rectum. 2003;46(7):851-859.
Soravia C, et al. Functional results after colectomy and ileorectal anastomosis for synchronous colorectal cancer. Am J Surg. 1999;178(6):528-531.
Copyright (c) 2024 Author (s). Published by Siddharth Health Research and Social Welfare Society
This work is licensed under a Creative Commons Attribution 4.0 International License.