Autologous Whole Blood Injection For COVID-19 Can Reduce Cytokine Storm and Severity of Illness

  • M. Christopher Consultant Anesthetist, Shifa Hospitals, Tirunelveli, Tamil Nadu, India
  • C. Jerriton Brewin Final year Post Graduate in M.D (DVL), Sri Venkateshwaraa Medical College Hospital and Research Centre, Pondicherry, India
  • Ramesh Babu Head of Department of Microbiology, Panimalar Medical College, Chennai, Tamil Nadu, India
  • M. Mohamed Arafath M.D (General Medicine), Medical Director, Shifa Hospital, Tirunelveli, Tamil Nadu, India
  • J. Auspas Assistant Professor, Department of General Medicine, Coimbatore Medical College, Coimbatore, Tamil Nadu, India
  • S R Tiruvalavan M.D. (Pharmacology)., M.B.A Lead Clinical Research, Shanmuga Hospital, Salem, Tamil Nadu, India
Keywords: Autologous whole blood, Autohemotherapy, Covid19 treatment

Abstract

Autologous whole blood injection is used for various indications. It has an immunomodulatory action on the immune system. A randomized controlled two-arm study was conducted to determine IL-6 levels, CT changes and mortality among adult COVID-19 patients. The trial included 30 patients divided into two groups. The interventional group received 2 doses of 2.5 ml of autologous whole blood injection spaced 2 days apart. There was a statistically significant reduction in IL-6 levels on day 6 in the group receiving treatment. CT score improved in patients who received treatment. No cases of mortality were reported in the treatment group. Autologous whole blood injection can be used as a simple, low-cost adjuvant in the treatment of adult COVID-19 patients, regardless of disease severity.

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How to Cite
1.
M. Christopher, C. Jerriton Brewin, Ramesh Babu, M. Mohamed Arafath, J. Auspas, S R Tiruvalavan. Autologous Whole Blood Injection For COVID-19 Can Reduce Cytokine Storm and Severity of Illness. Int J Med Res Rev [Internet]. 2021Jun.9 [cited 2021Jun.18];9(3):141-5. Available from: https://ijmrr.medresearch.in/index.php/ijmrr/article/view/1289
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Brief Report