Psychiatric manifestations of HIV disease

  • Dr. K. Rameshboobathi Associate Professor, Department of Psychiatry, Government Theni Medical College & Hospital, Theni, Tamil Nadu, India
  • Dr. N. Rajeshkannan Senior Resident, Government Institute of Psychiatric Medicine, Research & Rehabilitation, Theni, Tamil Nadu, India
Keywords: Adjustment disorder, Depression, Dementia, HIV, Mild cognitive dysfunction, Suicide

Abstract

Background: The appearance of AIDS on the medical and social scene in the early 1980 has been followed by worldwide spread of the disease and escalating numbers of persons affected. the first case was detected in 1984. For the first time in a worldwide epidemic, it has been necessary to try to change fundamental aspects of the human behavior by education and the dissemination of knowledge about psychiatric manifestations.

Aim: To find out the psychiatric manifestations of HIV disease.

Methods & Materials: 37 patients and 20 controls were taken up for evaluation of psychopathology. It’s a prospective study. Sociodemographic proforma, Socioeconomic Scale, Trail making A & B tests, color cancellation test, Raven's progressive matrices, Wechsler scale for memory, Linguistic fluency test were used.

Results: Persons with HIV were having psychiatric manifestations like, Adjustment disorders, Depression, suicide, schizophrenia, Mild cognitive impairment to Dementia were noted among HIV and associated illnesses.

Conclusion: Proper treatment adherence, counselling, follow up will improve the patient’s wellbeing.

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References

Goethe KE, Mitchell JE, Marshall DW, Brey RL, Cahill WT, Leger GD, et al. Neuropsychological and neurological function of human immunodeficiency virus seropositive asymptomatic individuals. Arch Neurol. 1989; 46(2): 129-133. doi: https://doi.org/10.1001/archneur.1989.00520380029008.

Goldmier D. Psychosocial aspects of AIDS. Br J Hosp Med. 1992;37(3):232-240.

Miller EN, Satz P, Visscher B. Computerized and conventional neuropsychological assessment of HIV‐1‐infected homosexual men. Neurol. 1991;41(10): 1608-1616. doi: https://doi.org/10.1212/WNL.41.10.1608

Perkins DO, Stern RA, Golden RN, Murphy C, Naftolowitz D, Evans DL. Mood disorders in HIV infection: prevalence and risk factors in a nonepicenter of the AIDS epidemic. Am J Psychiatry. 1994;151 (2): 233-236. doi: https://psycnet.apa.org/doi/10.1176/ajp.151.2.233.

Catalan J, Klimes I, Day A, Garrod A, Bond A, Gallwey J. The psychosocial impact of HIV infection in gay men. A controlled investigation and factors associated with psychiatric morbidity. Br J Psychiatry. 1992; 161:774-778. doi: https://doi.org/10.1192/bjp.161.6.774.

Brown GR, Rindell JR, Mcmars SE. Kendall SN, Zachary R, Temoshok L. Prevalence of psychiatric disorders in early stages of HIV infection. Psychosom. Med 1992;54(5):588-601.

Sabhesan S, Edwin T, Nammalvar N, Nageswari A. New-onset psychosis in AIDS. Indian J Psychiatry. 1998; 40(4):383-385.

Marzuk PM, Tierney H, Tardiff K, Gross EM, Morgan EB, Hsu MA, et al. Increased risk of suicide in persons with AIDS. JAMA. 1988;259(9):1333-1337. doi: https://doi.org/10.1001/jama.1988.037200900230288.

Wiley CA. Pathology of neurologic disease in AIDS. Psychiatric Clin North AM. 1994;17(1):1-15.

Brew BJ, Rosenblum M, Price RW. AIDS dementia complex and primary HIV brain infection. J Neuroimmunol. 1988; 20 (2-3): 133-140. doi: https://doi.org/10.1016/0165-5728(88)90144-0

Pajeau AK, Román GC. HIV encephalopathy and dementia. Psychiatr Clin North Am.1992;15(2):455-466

Atkinson JH, Grant I. Natural history of neuro-psychiatric manifestations of HIV disease. Psychiatr Clin North Am. 1994;17(1):17-33.

Wilkie FL, Eisdorfer C, Morgan R,Loewenstein DA, Szapocznik J. Cognition in early human immune-deficiency virus infection. Arch Neurol. 1990;47(4): 433-440.doi: https://doi.org/10.1001/archneur.1990.00530040085022.

Riedel RR, Helmstaedter C, Bülau P, Durwen HF, Brackmann H, Fimmers R, et al. Early signs of cognitive deficits among human immunodeficiency virus‐positive hemophiliacs. Acta Psychiatrica Scandinavica. 1992; 85(4): 321-326. doi: https://doi.Org/10.1111/j.1600-0447.1992.tb01476.x.

Lunn, S, Skydsbjerg M, Schulsinger H, Parnas J, Pederson C, Mathiesen I. A Preliminary report of the neuropsychological sequeale of human immune-deficiency virus. Arch Gen Psychiat. 1991 48.139-142.

Perry S, Jacobsberg L, Fishman B. Suicidal ideation and HIV testing. Jama. 1990;263(5):679-682. doi: https://doi.org/10.1001/jama.1990.03440050073036.

Stern, Y. Neuropsychological evaluation of the HIV Patients. The Psychiatric Clinics of North Am. 1994; 17:125-134.

Grant I, Atkinson JH, Hesselink JR, Kennedy CJ, Richman DD, Spector SA, et al. Evidence for early central nervous system involvement in the acquired immunodeficiency syndrome (AIDS) and other human immunodeficiency virus (HIV) infections. Studies with neuropsychologic testing and magnetic resonance imaging. Ann Intern Med. 1987;107(6):828-836. doi: https://doi.org/10.7326/0003-4819-107-6-828.

Maj M, Satz P, Janssen R, Zaudig M, Starace F, D'Elia L, et al. WHO Neuropsychiatric AIDS study, cross-sectional phase II. Neuropsychological and neurological findings. Arch Gen Psychiatry. 1994; 51 (1) : 51-61. doi: https://doi.org/10.1001/archpsyc.1994.03950010051007.

CITATION
DOI: 10.17511/ijmrr.2019.i05.11
Published: 2019-10-31
How to Cite
1.
K. R, N R. Psychiatric manifestations of HIV disease. Int J Med Res Rev [Internet]. 2019Oct.31 [cited 2024Dec.23];7(5):422-9. Available from: https://ijmrr.medresearch.in/index.php/ijmrr/article/view/1088
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