Study of fine needle aspiration cytology evaluation of peripheral lymph nodes

  • Dr. Prosenjit Gayen Assistant Professor, Department of Pathology, Malda Medical College, Malda, West Bengal, India
  • Dr. Saswata Ghosh Assistant Professor, Department of Chest Medicine, Malda Medical College, Malda, West Bengal, India
  • Dr. Subhrajyoti Naskar Assistant Professor, Department of Community Medicine, Malda Medical College, Malda, West Bengal, India
Keywords: FNAC, Granulomatous lymphadenitis, Lymph node, Reactive hyperplasia

Abstract

Introduction: Lymph nodes are an integral component of the immune system and their enlargement is commonly noted in clinical practice in a wide spectrum of diseases, including infections like tuberculosis and malignancy. FNAC is an important diagnostic tool for rapid evaluation of mainly superficial lesions, especially of lymph nodes. It is cost effective, relatively less traumatic, and enables the pathologist to provide the clinician with a diagnosis in a very short time, and hence is ideal especially for OPD patients.

Objectives: 1. To study the age and sex distribution of the patients of FNAC of peripheral lymph node. 2. To study the spectrum of diseases diagnosed on FNAC of peripheral lymph nodes.

Methods: Cross-sectional hospital based Observational study. Total 50 patients who had superficial lymphadenopathy were included in this study. Male patients were 21 (42%) and Female patients were 29 (58%). FNAC was performed on this 50 patients. Diagnosis was made by light Microscopy. Result was tabulated and statistical analysis was done.

Results: Male patients were 21 (42%) and Female patients were 29 (58%). 50 % patients were in the age group of 21 to 40 years. Reactive hyperplasia was 46% and Granulomatous lymphadenitis was 18%. Cervical lymph nodes were most commonly involved.

Conclusion: FNAC is a simple, quick, low cost, minimally invasive and easy diagnostic procedure which is very much helpful in the diagnosis of diseases causing superficial lymphadenopathy in all age groups. Reactive hyperplasia of lymph node was the most common cytological diagnosis followed by Granulomatous lymphadenitis.

Downloads

Download data is not yet available.

References

Vimal S, Dharwadkar A, Chandanwale SS, Vishwanathan V, Kumar H. Cytomorphological study of lymph node lesions: A study of 187 cases. Med J Dr. DY Patil University; 9(1):43.DOI: https://doi.org/10.4103/0975-2870.172428

Malaker D, Jajoo ILN, Swarup K, Gupta OP, Jain AP, Poflee VW. A clinical evaluation of fine Needle aspiration cytology in the diagnosis of lymphade-nopathy. Ind J Tub. 1991:17-9.

Shah PC, Patel CB, Bhagat V, Modi H. Evaluation of peripheral lymphadenopathy by fine needle aspiration cytology; a one year study at a tertiary centre. Int J Res Med Sci. 2016;4(1):120-5. DOI: http://dx.doi.org/10.18203/2320-6012.ijrms20160016

Chawla N, Nandini NM. FNAC in lymph node disorders a hospital study in Southern India. J Cytol. 2007; 24(2):105-7.

Qadri SK, Hamdani NH, Shah P, Lone MI, Baba KM. Profile of lymphadenopathy in Kashmir valley: a cytological study. Asian Pac J Cancer Prev. 2012; 13 (8): 3621-5. DOI: https://doi.org/10.7314/APJCP.2012.13.8.3621

Wilkinson AR, Mahore SD, Maimoon SA. FNAC in the diagnosis of lymph node malignancies: A simple and sensitive tool. Indian J Med Paediatr Oncol. 2012; 33 (1):21-4. DOI: https://doi.org/10.4103/0971-5851.96964.

Pandit AA, Candes FP, Khubchandani SR. Fine needle aspiration cytology of lymph nodes. J Postgrad Med. 1987;33(3):134-6.

Gupta RK, Naran S, Lallu S, Fauck R. The diagnostic value of fine needle aspiration cytology (FNAC) in the assessment of palpable supraclavicular lymph nodes: a study of 218 cases. Cytopathology. 2003;14(4):201-7. DOI: https://doi.org/10.1046/j.1365-2303.2003.00057.x

Duraiswami R, Margam S, Chandran P, Prakash A. Spectrum of pathologies on FNAC evaluation of peripheral lymph nodes at a tertiary care center in hyderabad: a retrospective study Int J Adv Med. 2017;4(1):27-33. DOI: http://dx.doi.org/10.18203/2349-3933.ijam20164703

Shrivastav A, Shah HA, Agarwal NM, Santwani PM, Srivastava G. Evaluation of peripheral lympha-denopathy by fine needle aspiration cytology. A three year study at tertiary center. Journal of Dr NTR University of Health Sciences. 2014;3(2):86-91. DOI: https://doi.org/10.4103/2277-8632.134834

Mohanty R, Wilkinson A. Utility of fine needle aspiration cytology of lymph nodes. IOSR J Dent Med Sci. 2013;8(5):13-8.

Pandey P, Dixit A, Mahajan NC. The diagnostic value of FNAC in assessment of superficial palpable lymph nodes: a study of 395 cases. Al Ameen J Med Sci. 2013;6(4):320-7.

Kumar H, Chandanwale SS, Gore CR, Buch AC, Satav VH, Pagaro PM. Role of fine needle aspiration cytology in assessment of cervical lymphadenopathy. Med J Dr DY Patil University. 2013; 6(4): 400-4. DOI: https://doi.org/10.4103/0975-2870.118287

Shilpa G, Nataraju G. Pattern of lymph node diseases in a tertiary level referral center: a cytological study of 943 cases. Inter Biol Med Res. 2013; 4(3): 3448-52.

Gojiya P, Goswami A, Shah S. Evaluation of Fine Needle Aspiration Cytology of Cervical Lymphadeno-pathies at Tertiary Care Center. Annals of Patho and Lab Med. 2018;5(1):22-27.

Shakya G, Malla S, Shakya KN, Shrestha R. A study of FNAC of cervical lymph nodes. J Nepal Health Res Counc 2009; 7 (1):1-5. DOI: https://doi.org/10.3126/jnhrc.v7i1.2267

Sharma R.I, Dharaiya C.M. Study of fine needle aspiration cytology of lymphadenopathy in tertiary care centre of Ahmedabad, Gujarat.Trop J Path Micro 2018; 4 (3):258-264.DOI: 10.17511/jopm.2018.i3.04.

Bhavani C, Neeraja M, Varalakshmi KP, Ramana Babu PV, Chaitanya B, Sravani P. Role of FNAC in the diagnosis of cervical lymphadenopathy. Int J Med Res Rev 2014;2:599-603.DOI: 10.17511/ijmrr.2014.i06.015.

Patel MM, Italiya SL, Dhandha ZB, Dudhat RB, Kaptan KR, Shah MB et al. Study of metastasis in lymphnodes in FNAC: Our institutional experience. Int J Res Med Sci 2013;1:451-4. DOI: https://doi.org/10.5455/2320-6012.ijrms20131128 .

Ghartimagar D, Ghosh A, Ranabhat S, Shrestha MK, Narasimhan R, Talwar OP. Utility of fine needle aspiration cytology in metastatic lymph nodes. J Pathol Nepal 2011;1:92-5.

Badge SA, Ovhal AG, Azad K, Meshram AT. Study of fine-needle aspiration cytology of lymph node in rural area of Bastar District, Chhattisgarh. Med J DY Patil Univ 2017;10(2):143-8 DOI: http://www.mjdrdypu.org/text.asp?2017/10/2/143/202097

CITATION
DOI: 10.17511/ijmrr.2019.i04.02
Published: 2019-08-31
How to Cite
1.
Gayen P, Ghosh S, Naskar S. Study of fine needle aspiration cytology evaluation of peripheral lymph nodes. Int J Med Res Rev [Internet]. 2019Aug.31 [cited 2024Apr.26];7(4):259-65. Available from: https://ijmrr.medresearch.in/index.php/ijmrr/article/view/1067
Section
Original Article