Evaluation of corticosteroid use in outpatient department of dermatology of a tertiary care teaching hospital: a prospective observational study

  • Dr. Haiya J. Sheth Resident, Department of Pharmacology, Smt. N.H.L. Municipal Medical College, Ellisbridge, Ahmedabad, Gujarat, India
  • Dr. Raju G. Chaudhary Professor & Head, Department of Dermatology, Smt. N.H.L. Municipal Medical College, Ellisbridge, Ahmedabad, Gujarat, India
  • Dr. Supriya D. Malhotra Professor & Head, Department of Pharmacology, Smt. N.H.L. Municipal Medical College, Ellisbridge, Ahmedabad, Gujarat, India
Keywords: Betamethasone, Corticosteroids, Dermatology, Potency, Topical, WHO drug prescribing indicators

Abstract

Background: Corticosteroids are widely prescribed drugs in dermatology. Rational prescribing of steroids is important for best therapeutic outcome at lowest possible dose. A study was carried out at a tertiary care teaching hospital in order to evaluate the use of corticosteroids which provided a picture of trends in the usage of corticosteroids in dermatology at that set-up.

Materials and Methods: This prospective, observational study was carried out in department of dermatology for 1 year after ethical approval. Data was analysed for parameters related to corticosteroids, their potency, WHO drug prescribing indicators, effectiveness as well as effects of corticosteroids on quality of life of patients. Statistical analysis was done using Microsoft Excel Office 365.

Results: In the 223 patients, 44.84% patients belonged to 21-40 years age group. Mostcommon indication was eczema in 29.15% cases. Topical betamethasone (25.11%) and oral prednisolone (20.17%) were most frequently prescribed. 95/140 topical steroids prescribed were super highly potent. Among concomitant drugs, a majority of 38% were antihistaminics. Degree of polypharmacy showed 04 drugs in a majority (43.15%) of prescriptions. Only 6.27% drugs were prescribed by generic name.

Conclusion: Corticosteroids were beneficial to a large no. of patients. Initial usage of low potency steroids topically wherever possible can be emphasized. WHO drug prescribing indicators analysis indicated the need to adhere to WHO guidelines as well as prescribing drugs by generic name. To maintain a balance between judicious use and frequent abuse with corticosteroid is important along with physician’s vigilance and patient education.

Downloads

Download data is not yet available.

References

Jain S, Barambhe MS, Jain J, Jajoo UN, Pandey N. Prevalence of skin diseases in rural Central India: A community-based, cross-sectional, observational study. J Mahatma Gandhi Inst Med Sci. 2016;21(2):111-115. DOI: http://www.jmgims.co.in/text.asp?2016/21/2/111/189537

Saravanakumar RT, Prasad GS, Ragul G, Mohanta GP, Manna PK, Moorthi C. Study of prescribing pattern of topical corticosteroids in the department of dermatology of a multispecialty tertiary care teaching hospital in South India. Int. J. Res. Pharm. Sci. 2012;3(4):685-687. DOI: 10.5455/ijmsph.2015.17052015351

Wahane PA, Jagtap R, Ghongane B. Evaluation of Corticosteroid Use Pattern in Steroid Responsive Dermatological Conditions. Int J Med Res Health Sci. 2016;5(1):82-86. DOI: http://dx.doi.org/10.5958/2319-5886.2016.00017.5

Verma SB. Topical corticosteroid misuse in India is harmful and out of control. BMJ. 2015 Nov 25;351:h6079. DOI: https://doi.org/10.1136/bmj.h6079.

Sinha A, Kar S, Yadav N, Madke B. Prevalence of topical steroid misuse among rural masses. Indian J Dermatol. 2016;61(1):119. DOI: https://dx.doi.org/10.4103%2F0019-5154.174081

Biswas NR, Jindal S, Siddiquei MM, Siddiquei MM, Maini R. Patterns of prescription and drug use in ophthalmology in a tertiary hospital in Delhi. Br J Clin Pharmacol. 2001;51(3):267-9. DOI: 10.1046/j.1365-2125.2001.00350.x.

Bylappa BK, Patil RT, Pillai RT. Drug prescribing pattern of topical corticosteroids in dermatology unit of a tertiary-care hospital. Int J Med Sci Public Health. 2015;4(12):1702-1707. DOI: https://doi.org/10.5455/ijmsph.2015.17052015351.

Nerukar RP, Kokane MR, Mehta MN. Study of prescribing pattern of topical corticosteroids in dermatology outpatient department in a tertiary care hospital in India. Int J Basic Clin Pharmacol. 2016;5(5):2194-2198. DOI: http://dx.doi.org/10.18203/2319-2003.ijbcp20163261

Mukherjee S, Era N, Banerjee G, Tripathi SK. Assessment of corticosteroid utilization pattern among dermatology outpatients in a tertiary care teaching hospital in Eastern India. Int J Green Pharma. 2016;10(4):S178-S182. DOI: http://dx.doi.org/10.22377/ijgp.v10i04.780

Adhikari K, Bezbaruah BK. Evaluation of prescription pattern of steroid in dermatology adverse effects with steroids use. Int J Current Res. 2017;;9(3):48419-48422.

Abraham MS, Sajeeth CI, Sreeja PA, Abraham BT. Drug Utilization Evaluation of Corticosteroids in Dermatology Department of a Tertiary Care Teaching Hospital at Palakkad, Kerala. IJHSR. 2016;6(6):130-136.

Jaiswal MK, Chakrawarty R, Sharma S, Sachdev D, Sharma R, Sajidali S. Prescription audit of Corticosteroids in Dermatology OPD of a tertiary care teaching hospital of tribal region of central-south India. Int J Biomed Res. 2017;8(1):20-25. DOI: https://dx.doi.org/10.7439/ijbr.v8i1.3830

Manju, Saravanam R, Balan S, Menon R, David BG. Study of prescribing pattern of topical corticosteroids in dermatology outpatient department in a Tertiary Care Hospital in Puducherry. Int J Pharmacol Res. 2018;8(1):01-05. DOI: https://doi.org/10.7439/ijpr.v8i1.4576

Aryal A, Kunwar K, Shavdar S, Kharel S, Ramasamy R, Shashidhar G et al. Study on Steroid Utilization Pattern in a Tertiary Care Teaching Hospital. Indian J Pharma Pract. 2017;10(2):96-103. DOI: https://dx.doi.org/10.5530/ijopp.10.2.19

Purushotham K, Eesha B R. Prescription Trend of Topical Corticosteroids in Outpatient of Dermatology in a Tertiary Care Hospital in Tumakuru, Karnataka. Int J Pharmacol and Clin Sci. 2016;5(3):77-72. DOI: http://dx.doi.org/10.5530/ijpcs.5.3.3

Thakur PK, Majid A, Shramik M, Kumar S. A Prospective Study on Drug Utilization Evaluation of Corticosteroids among Out-Patients of Teaching Hospital. International Journal of Pharmacy Teaching & Practices. 2015:6(4):2630-2634.

Gambre R, Khobragade A, Jalikar K, Patel S, Gaidhane S. Analysis of Prescribing Pattern of Drugs Among Patients Attending Dermatology Outpatient Department of a Tertiary Care Hospital. EJPMR. 2018;5(3):259-273.

Sung JY, Roh MR, Kim SC. Quality of Life Assessment in Korean Patients with Pemphigus. Ann Dermatol. 2015 Oct;27(5):492-8. DOI: https://doi.org/10.5021/ad.2015.27.5.492. Epub 2015 Oct 2.

Sheth HJ, Rathod SP, Chaudhary RG, Malhotra SD, Patel PR. Tinea incognito with unjustified use of potent Topical Corticosteroids: a case series. Int J Basic Clin Pharmacol 2017;6(8):2087-90. DOI: http://dx.doi.org/10.18203/2319-2003.ijbcp20173301

Evaluation of corticosteroid use in outpatient department of dermatology of a tertiary care teaching hospital: a prospective observational study
CITATION
DOI: 10.17511/ijmrr.2019.i03.16
Published: 2019-06-30
How to Cite
1.
J. Sheth H, G. Chaudhary R, D. Malhotra S. Evaluation of corticosteroid use in outpatient department of dermatology of a tertiary care teaching hospital: a prospective observational study. Int J Med Res Rev [Internet]. 2019Jun.30 [cited 2024Dec.23];7(3):243-52. Available from: https://ijmrr.medresearch.in/index.php/ijmrr/article/view/1066
Section
Original Article