A study of serum magnesium level in hypothyroid cases in a tertiary care hospital, Perambalur

  • Dr. I. Vijayapriya Assistant Professor, Biochemistry, Government Head Quarters Hospital, Perambalur, Tamilnadu, India
  • Dr. S. Saravanan Senior Civil Surgeon, Government Head Quarters Hospital, Perambalur, Tamilnadu, India
Keywords: Serum magnesium, Hypothyroidism, Thyroid function test

Abstract

Magnesium is an incredibly vital mineral found in the human body. Magnesium clearly affects the entire body and naturally will interact with thyroid functions, both directly and indirectly.

Objectives: To assess the levels of serum magnesium in patients with hypothyroidism and its correlation with TSH levels.

Methodology: An observational study consists of 174 cases of hypothyroidism were selected. All patients with hypothyroidism, newly diagnosed with age above 18years were included, all patients with malignancy, multiple endocrine disorder, CKD and patients supplemented with minerals were excluded in the study. Thyroid function and serum magnesium levels were done and analyzed in these patients.

Results: In our study mean serum magnesium level in hypothyroid cases was 2.18±0.02 mg/dl. Our study done with a follow up of thyroid function and serum magnesium level in hypothyroidism after supplementation with thyroid hormone and diet supplementation for magnesium showed a significant improvement which reciprocate the incidence of hypo magnesium in hypothyroidism and which is inversely proportionate to TSH levels which was not statistically significant.

Conclusion: The alteration of serum magnesium level in hypothyroidism was not established in our study statistically.

Downloads

Download data is not yet available.

References

P. Reed, Terry FD, Martin JS, Ian DH. Thyroid physiology and diagnostic evaluation of patients with thyroid disorders. In: Henry MK, Shlomo M, Kenneth SP, P Reed, editors. Williams Textbook of Endocrinology. 11th ed. Philadelphia: Saunders Elsevier; 2008 pp 1002.

Taylor PK. Thyroid disease: Hypothyroidism and Goitre. Medicine Update1993;1:357-356.

Vanderpump MP. The epidemiology of thyroid disease. Br Med Bull. 2011;99:39-51. doi: https://doi.org/10.1093/bmb/ldr030.

Galesanu C, Linsic N, Teslaru R, Apostu L, Zbranca E. Lipid profile in a group of hypothyroid patients vs treated hypothyroid patients. Rev Med Chir Soc Med Nat Lasi 2004;108(3):554-560.

Pearce EN. Hypothyroidism and dyslipidemia: modern concepts and approaches. Curr Cardiol Rep. 2004 Nov;6 (6):451-6.

Shivaleela MB, Poornima RT and Jayaprakash MDS. Serum Calcium and Phosphorouslevels in thyroid dysfunction. Indian Journal of Fundamental and Applied Life Sciences 2012;2(2):179-183.

Auwerx J, Bouillon R. Mineral and bone metabolism in thyroid disease: a review. Q J Med. 1986 Aug;60 (232):737-52.

Abbas MM, Mahmoud AH and El-Desouky W. Biochemical Changes in Serum Lipid Fractions, Calcium, Magnesium and Phosphorous Levels in Women with Subclinical Hypothyroidism. Nature and Science 2013;11(5):113-118.

Laura HM, Jeffrey SB. The Renal Manifestations of Thyroid Disease. J Am SocNephrol 2012;23:22–26. [Google].

McCaffrey C, Quamme GA. Effects of thyroid status on renal calcium and magnesium handling. Can J Comp Med. 1984 Jan;48(1):51-7.

Mane AY, Bhagwat VR. Assessment of some biochemical markers of bone turnover in thyroid dysfunction state. International Journal of Pharma and Bio Sciences 2012; 3(3): B126 –133.

Mukesh G Gohel, Aashka M Shah, Akash M. Shah, Jemil S Makad. A Study of Serum Calcium, Magnesium and Phosphorous Level in Hypothyroidism Patients. Int J Mcd He11iihSci. Oct 2014,Vol-3;Issue-4.

Kavitha MM, Chandrashekharyya SH, SV Kashinakunti, Sunitha H, Neela BM, Sanjeev Ratna. Alteration in levels of Serum calcium, phosphorous and magnesium in patients of Hypothyroidism. Int) Bioi Med Res. 2014; 5(4): 4594-4596.

Arvind Bharti, Shailaza Shrestha, Rahul Rai and Mukesh Kumar Singh. Assessment of serum minerals and electrolytes in thyroid patients. International Journal of Advances in Scientific Research 2015; 1(06): 259-263.

Susanna TY, Sagayaraj A, Shashidharkn, Gomathi M, Mahesh V. A correlative study of thyroid profile and mineral status in patients with hypothyroidism - a hospital based case control study. Asian j pharm clin res, vol 9, issue 3, 2016, 292-294.

A study of serum magnesium level in hypothyroid cases in a tertiary care hospital, Perambalur
CITATION
DOI: 10.17511/ijmrr.2019.i03.08
Published: 2019-06-30
How to Cite
1.
I. V, S. S. A study of serum magnesium level in hypothyroid cases in a tertiary care hospital, Perambalur. Int J Med Res Rev [Internet]. 2019Jun.30 [cited 2024Nov.8];7(3):195-9. Available from: https://ijmrr.medresearch.in/index.php/ijmrr/article/view/1058
Section
Original Article