A study on the non-infectious complications of continuous ambulatory peritoneal dialysis

  • Dr. Niveditha S­. Assistant Professor, Department of Medicine, Sri Devaraj Urs Medical College, Kolar, Karnataka state, India
  • Dr. Aravind S. Postgraduate Student, Department of Medicine, Regional Institute of Medical Science, Imphal, Manipur State, India
  • Dr. L.K. Sharatchandra Singh Professor, Department of Medicine Regional Institute of Medical Science, Imphal, Manipur State, India
Keywords: CAPD, ESRD, Non-infectious complications, Omental wrap, Catheter tip migration

Abstract

Introduction: Patients with end-stage renal disease (ESRD) are treated with hemodialysis (HD) or continuous ambulatory peritoneal dialysis (CAPD).Non-infectious complications of CAPD are increasing in relative importance due to success in decreasing the rate of peritonitis.

Aims and objectives: Our aim was to study the non-infectious complications in patients of ESRD on CAPD and to study the impact of the non-infectious complications in the survival of CAPD catheters. Materials and Methods: A prospective study has been conducted at Regional institute of medical science, Imphal in a total of 71patients of ESRD who are already on CAPD or newly diagnosed ESRD who have undergone CAPD catheter implantation. Their detailed history, clinical examination and relevant laboratory investigations were done and the different non-infectious complications were identified and analysed.

Result: Out of the 71 patients studied 39 patients had complications like hypokalemia (15 patients), omental wrap (10 patients), catheter tip migration (6 patients), haemoperitonium (2 patients), hydrothorax (2patients), exit site leak(2patients), abdominal wall edema (1patient), catheter block(1patient).

Conclusion: In our study the most common non-infectious complication was hypokalemia followed by omental wrap and catheter tip migration. Knowledge about the common prevalent non-infectious complications of CAPD alerts the treating doctor to take up the specific corrective steps at an earlier stage, thus preventing the morbidity associated with the same. We conclude that the majority of non-infectious complications in these patients were treatable and did not interfere with the catheter survival.

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References

Moeller S, Gioberge S, Brown G. et al. ESRD patients in 2001: global overview of patients, treatment modalities and development trends. Nephrol Dial Transplant. 2002 Dec;17(12):2071-6. DOI: https://doi.org/10.1093/ndt/17.12.2071.

Schaubel DE, Blake PG, Fenton SS. Trends in CAPD technique failure: Canada, 1981-1997. Perit Dial Int. 2001 Jul-Aug;21(4):365-71.

Mujais S, Story K. Peritoneal dialysis in the US: evaluation of outcomes in contemporary cohorts. Kidney Int Suppl. 2006 Nov;(103):S21-6.

Kidney International Supplements (2013) 3, 19–62.

Abbott KC, Glanton CW, Trespalacios FC, et al. Body mass index, dialysis modality, and survival: analysis of the United States Renal Data System Dialysis Morbidity and Mortality Wave II Study. Kidney Int. 2004 Feb; 65 (2):597-605. DOI: https://doi.org/10.1111/j.1523-1755.2004.00385.x.

Mekki MO, Fedail HM, Ali EMA, Mohammed BA, Al-Sanousi H, Elamin S et al. Non-infectious Complications of Peritoneal Dialysis among Sudanese Patients: Five Years Experience. Arab J Nephrol Transplant 2011;4(1):27-30.

Oreopoulos DG, Khanna R, Williams P, Vas SI. Continuous ambulatory peritoneal dialysis - 1981. Nephron. 1982;30(4):293-303.

Musso CG. Potassium metabolism in patients with chronic kidney disease (CKD), Part I: patients not on dialysis (stages 3-4). Int UrolNephrol. 2004;36(3):465-8.

Amerling R, Maele DV, Spivak H, et al. Laparoscopic salvage of malfunctioning peritoneal catheters. SurgEndosc. 1997 Mar;11(3):249-52.

Lee M, Donovan JF. Laparoscopic omentectomy for salvage of peritoneal dialysis catheters. J Endourol. 2002 May;16(4):241-4.

Kimmelstiel FM, Miller RE, Molinelli BM, et al. Laparoscopic management of peritoneal dialysis catheters. SurgGynecol Obstet. 1993 Jun;176(6):565-70.

Kavalakkat JP, Kumar S, Aswathaman K, Kekre NS. Continuous ambulatory peritoneal dialysis catheter placement: Is omentectomy necessary? UrolAnn 2010;2(3):107-9.

Prakash J, Sharath Chandra Singh LK, Shreenivas S, Ghosh B, Singh TB. Non infectious complications of continuous ambulatory peritoneal dialysis and their impact on technique survival. Indian J Nephrol 2011; 21(2): 112–15.

Marwa M, Mohammed A, Aicha B, Adil K, Ali I, Yassine N, Loubna B. Mechanical Complications of Peritoneal Dialysis. Open J Nephrol 2014; 4: 103-9.

Greenberg A, Bernardini J, Piraino BM, Johnston JR, Perlmutter JA. Hemoperitoneum complicating chronic peritoneal dialysis: single-center experience and literature review. Am J Kidney Dis1992; 19:252-256.

Harnett JD, Gill D, Corbett L, et al. Recurrent hemoperitoneum in women receiving continuous ambulatory peritoneal dialysis. Ann Intern Med. 1987 Sep;107(3):341-3.

Marel M, Zrůstová M, Stasný B, et al. The incidence of pleural effusion in a well-defined region. Epidemiologic study in central Bohemia. Chest. 1993 Nov;104(5):1486-9.

Leblanc M, Ouimet D, Pichette V. Dialysate leaks in peritoneal dialysis. Semin Dial. 2001 Jan-Feb;14(1):50-4.

Schmekal B. [Peritoneal dialysis in patients with high body-mass index]. Wien KlinWochenschr. 2005;117 Suppl 6:40-5. DOI: https://doi.org/10.1007/s00508-005-0495-8.

Bergström J, Lindholm B. Malnutrition, cardiac disease, and mortality: an integrated point of view. Am J Kidney Dis. 1998 Nov;32(5):834-41.

Stenvinkel P, Heimbürger O, Paultre F, et al. Strong association between malnutrition, inflammation, and atherosclerosis in chronic renal failure. Kidney Int. 1999 May;55(5):1899-911. DOI: https://doi.org/10.1046/j.1523-1755.1999.00422.x

Guérin AP, London GM, Marchais SJ, et al. Arterial stiffening and vascular calcifications in end-stage renal disease. Nephrol Dial Transplant. 2000 Jul;15(7):1014-21. DOI: https://doi.org/10.1093/ndt/15.7.1014

Milionis HJ, Elisaff MS, Karabina SAP, Bairaktari E, Tselepis AD, Siamopoulos KC: Plasma and Lp(a)-associated PAF-acetylhydrolase activity in uremic patients undergoing different dialysis procedures. Kidney Int 56: 2276–2281, 1999.20-6012.ijrms20162895.

A study on the non-infectious complications of continuous ambulatory peritoneal dialysis
CITATION
DOI: 10.17511/ijmrr.2019.i03.05
Published: 2019-06-30
How to Cite
1.
S. N, S. A, Singh LS. A study on the non-infectious complications of continuous ambulatory peritoneal dialysis. Int J Med Res Rev [Internet]. 2019Jun.30 [cited 2024Dec.23];7(3):176-81. Available from: https://ijmrr.medresearch.in/index.php/ijmrr/article/view/1055
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