@article{Bedi_Joshi_2020, title={Role of biochemistry, cytology, and biopsy in the etiological diagnosis of pleural effusion- a clinical study}, volume={8}, url={https://ijmrr.medresearch.in/index.php/ijmrr/article/view/1196}, DOI={10.17511/ijmrr.2020.i03.07}, abstractNote={<p>Introduction:Pleural effusion is the most common pleural disorder. It refers to excessive or abnormal accumulation of fluid in the pleural space. It is a commonly occurring medical problem caused by various pathological conditions. To treat patients appropriately, it is important to establish an accurate etiological diagnosis.</p> <p>Material and Method: This is an observational study conducted at a tertiary health care center. The pleural effusion was assessed clinically, biochemically, bacteriologically, cytologically, and histopathologically.</p> <p>Result: Tuberculosis was the most common etiology, followed by malignancy. A pleural biopsy was done in 70 patients. Pleural tissue was obtained in 65 cases. On histopathology,Malignancy was diagnosed in 15, tuberculosis in 35, and non-specific inflammation in 13 cases. Out of 35 histological proven tuberculosis cases, 26 cases had adenosine de-aminase (ADA) more than 70 u/l.</p> <p>Conclusion:Every pleural effusion is not due to tuberculosis but can be due to other causes, malignancy should always be excluded. Pleural fluid cytology and biopsy can give a definite diagnosis in a significant number of cases of pleural effusion. Tuberculosis is still the most common cause of pleural effusion followed by malignancy.</p&gt;}, number={3}, journal={International Journal of Medical Research and Review}, author={Bedi, Manan and Joshi, Nalin}, year={2020}, month={Jun.}, pages={259-264} }